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Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure

Key facts

Where
Aurora, United StatesSee the site

Where in United States

  • Rocky Mountain Regional VA Medical Center, Aurora, COAurora, United StatesNo longer taking part

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  2. Are travel costs paid?
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  4. What happens if I want to stop?
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Trial details

Who runs it
VA Office of Research and Development
Trial code
NCT07714239
Record updated
17 September 2026
Original description
Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge. This study tests whether a team of clinical pharmacists and cardiologists, working virtually, can improve heart failure medication prescribing for Veterans at VA medical centers. The pharmacist and cardiologist team reviews patient records and provides recommendations to the treating doctors and primary care providers caring for Veterans with heart failure. The goal is to increase use of guideline-recommended medications, which have been shown to improve survival, reduce hospitalizations, and improve quality of life.Read full original descriptionShow less

Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure (PATRIOT-HF) (QUE 25-018)

Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge. This study tests whether a team of clinical pharmacists and cardiologists, working virtually, can improve heart failure medication prescribing for Veterans at VA medical centers. The pharmacist and cardiologist team reviews patient records and provides recommendations to the treating doctors and primary care providers caring for Veterans with heart failure. The goal is to increase use of guideline-recommended medications, which have been shown to improve survival, reduce hospitalizations, and improve quality of life.

Inclusion: Admission to a VA medical center or VA-paid community hospital within the preceding 3 months with a primary diagnosis of heart failure; The primary study cohort will consist of those admitted to a VA medical center, while the secondary study cohort will consist of patients admitted to VA-paid community hospitals; Left ventricular ejection fraction ≤ 40%; Not on optimal guideline-directed heart failure medication classes or doses, as assessed in the electronic health record; Receiving care within one of the 6 participating VA medical centers.

Exclusion: Receiving comfort care measures alone or enrolled in hospice; Hemodynamic instability.

ClinicalTrials.gov NCT07714239