Tests a re-engagement program for adults with advanced HIV disease
Tests the ARC program in hospitalized adults with advanced HIV disease.
Plain-language title generated from the registry record
Registry title: Advanced HIV Re-engagement in Care
Key facts
- Where
- Lusaka, ZambiaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in hospital in Lusaka, Zambia, who are living with HIV and have advanced HIV disease.
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Advanced HIV: CD4 below 350 cells/mm3 or a WHO stage 3 or 4 event.
- Biomarker or test result
- CD4 below 350 cells/mm3 (or a WHO stage 3 or 4 event).
Main reasons for not taking part
- Planning to live outside Lusaka after leaving hospital
- Too sick to give informed consent
- Advanced cancer needing chemo or radiation, or referred to hospice (Kaposi Sarcoma is allowed)
- End stage kidney disease or end stage liver disease
- No access to a telephone, or currently in prison
This trial only enrols participants living with HIV. The registry sentence this rests on: Living with HIV
Read by machine on 9 November 2026.
Where in Zambia
- University Teaching HospitalLusaka, ZambiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Alabama at Birmingham
- Trial code
- NCT07720128
- Record updated
- 23 July 2026
- Original description
Adults who are hospitalized in Lusaka, Zambia, and found to have advanced HIV disease will be enrolled and randomly assigned to receive the ARC intervention or standard of care. All participants will then be followed through the end of the hospitalization and for up to 1 year after discharge from hospital.Read full original descriptionShow less
Advanced HIV Re-engagement in Care
Adults who are hospitalized in Lusaka, Zambia, and found to have advanced HIV disease will be enrolled and randomly assigned to receive the ARC intervention or standard of care. All participants will then be followed through the end of the hospitalization and for up to 1 year after discharge from hospital.
Inclusion: Living with HIV; Advanced HIV defined as CD4 <350 cells/mm3 or WHO stage 3 or 4 event; Currently admitted to study hospital's internal medicine department.
Exclusion: Known to have advanced cancer (defined as requiring chemo/radiation therapy or referred to hospice) other than Kaposi Sarcoma; Known to have end stage kidney disease; Known to have end stage liver disease; Planning to reside outside Lusaka after discharge; Too sick to provide informed consent; No access to a telephone; Currently incarcerated.