Exercise during dialysis sessions to improve posture in people on hemodialysis
Tests supervised exercise during dialysis for posture problems in adults on hemodialysis.
Plain-language title generated from the registry record
Registry title: The Effect of Intradialytic Exercise on Postural Abnormalities
Key facts
- Where
- Isfahan, IranSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07720401, who can take part
Where in Iran
- Pardis specialized wellness instituteIsfahan, IranTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Pardis Specialized Wellness Institute
- Trial code
- NCT07720401
- Record updated
- 1 September 2026
- Original description
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving maintenance hemodialysis. Participants will be randomized to either supervised intradialytic exercise plus usual care or usual care alone. The exercise program will be performed three times per week during scheduled hemodialysis sessions and will include postural correction exercises, resistance-band strengthening, core stabilization, stretching, breathing exercises, and seated aerobic cycling. The primary outcome will be change in thoracic kyphosis angle from baseline to Week 12. Secondary outcomes will include craniovertebral angle, balance, mobility, functional exercise capacity, gait speed, physical activity level, adherence, and adverse events. The findings may provide preliminary evidence on the feasibility, safety, and potential clinical value of incorporating postural correction exercises into routine hemodialysis care.Read full original descriptionShow less
Effects of Supervised Intradialytic Exercise Program on Postural Abnormalities in Maintenance Hemodialysis Patients: A Randomized Controlled Trial
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving maintenance hemodialysis. Participants will be randomized to either supervised intradialytic exercise plus usual care or usual care alone. The exercise program will be performed three times per week during scheduled hemodialysis sessions and will include postural correction exercises, resistance-band strengthening, core stabilization, stretching, breathing exercises, and seated aerobic cycling. The primary outcome will be change in thoracic kyphosis angle from baseline to Week 12. Secondary outcomes will include craniovertebral angle, balance, mobility, functional exercise capacity, gait speed, physical activity level, adherence, and adverse events. The findings may provide preliminary evidence on the feasibility, safety, and potential clinical value of incorporating postural correction exercises into routine hemodialysis care.
Inclusion: Age 18-80 years; Diagnosed with ESRD and receiving stable maintenance hemodialysis for at least 3 months at the participating center, with a dialysis frequency of three sessions per week; Confirmed presence of at least one postural abnormality (hyperkyphosis ≥53° in women or ≥55° in men, or CVA <53°) assessed at screening; Written informed consent obtained, indicating decision-making capacity and willingness to participate; Medical clearance from attending nephrologist to participate in supervised exercise during dialysis; Ability to sit upright in a dialysis chair and perform seated or supported standing exercises; Ability to communicate in Persian and understand study instructions.
Exclusion: Hemodynamic instability defined as systolic blood pressure <90 mmHg or >200 mmHg, or severe orthostatic hypotension, at screening or prior to exercise sessions; Scheduled kidney transplantation within the study period; Unstable cardiovascular status, including recent (within 3 months) myocardial infarction, unstable angina, decompensated congestive heart failure (NYHA Class III-IV), or uncontrolled arrhythmia; Active infection, acute febrile illness, or acute medical condition requiring hospitalization; Severe peripheral neuropathy or vascular disease (ABI <0.6) precluding lower limb exercise; Severe cognitive impairment (MMSE <18) preventing informed consent or adherence to exercise instruction; Uncontrolled diabetes mellitus with labile glycemic control (blood glucose <4 mmol/L or >22 mmol/L at dialysis session start); Severe musculoskeletal pain at rest or with minimal activity (Numeric Pain Rating Scale ≥7/10) that would preclude exercise participation; Inability to perform seated exercises, walk independently, or maintain upright posture; severe neurological disability; Recent fracture (within 6 months) of vertebral column, pelvis, or lower extremities; Dyspnea at rest or with activities of daily living corresponding to NYHA Class IV; Participation in a structured exercise program targeting postural correction, resistance, or balance training ≥3 times per week in the preceding 3 months; Pregnancy or planned pregnancy during the study period; Life expectancy <6 months as determined by the attending nephrologist.