Checking catheter contact during pulsed field ablation for paroxysmal atrial fibrillation
Tests how well a catheter touches heart tissue during ablation for atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Assessment of Catheter Tissue Contact in PFA
Key facts
- Where
- Ljubljana, SloveniaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07721948, who can take part
Where in Slovenia
- University Medical Centre LjubljanaLjubljana, SloveniaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Medical Centre Ljubljana
- Trial code
- NCT07721948
- Record updated
- 22 October 2026
- Original description
Pulmonary vein isolation remains the cornerstone of invasive treatment for atrial fibrlllation. Despite recent technological advances in the field of pulsed field ablation (PFA) pulmonary vein isolation durability and arrhythmia free success rates remain approximately at the level of previous years and the radiofrequency ablation era.Read full original descriptionShow less
Assessment of Electrode-tissue Contact and Pulmonary Vein Isolation Durability After Pulsed Field Ablation With a Circular "Single Shot" Catheter in Patients With Paroxysmal Atrial Fibrillation
Pulmonary vein isolation remains the cornerstone of invasive treatment for atrial fibrlllation. Despite recent technological advances in the field of pulsed field ablation (PFA) pulmonary vein isolation durability and arrhythmia free success rates remain approximately at the level of previous years and the radiofrequency ablation era.
Isolation durability during PFA procedures might be enhanced by:
1. Intraprocedural monitoring contact of catheter electrode to atrial tissue. 2. Intraprocedural assessment of the transmurality of irreversible electroporation lesion.
The aim of our study is to use intracardiac electrogram (iEGM) based analysis for assessment of catheter-tissue contact and PFA lesion durability.
Inclusion: Patients with electrocardiographically documented paroxysmal atrial fibrillation (AF), defined according to the European Heart Rhythm Association (EHRA) guidelines.
Exclusion: Previous left atrial ablation; Acute life-threatening illness; Age >80 years; Contraindication to pulsed field ablation in the left atrium (e.g., presence of a left atrial appendage occlusion device); Contraindication to undergoing the procedure under general anesthesia; Markedly enlarged left atrium (diameter >50 mm on echocardiography, LAVI >50 mL/m²); Life expectancy <1 year; Presence of left atrial thrombus; Secondary atrial fibrillation.