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Underwater endoscopic removal of small type I gastric neuroendocrine tumors

Tests underwater endoscopic removal of small stomach neuroendocrine tumors in adults.

Plain-language title generated from the registry record
Registry title: Safety and Efficacy of Underwater Endoscopic Mucosal Resection for Type I Gastric Neuroendocrine Tumors Measuring 5-9 mm

Key facts

Where
Hyderabad, IndiaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07728292, who can take part

Where in India

  • Asian Institute of Gastroenterology/AIG HospitalsHyderabad, IndiaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Asian Institute of Gastroenterology, India
Trial code
NCT07728292
Record updated
27 July 2026
Original description
Study objectives:Read full original descriptionShow less

Safety and Efficacy of Underwater Endoscopic Mucosal Resection for Type I Gastric Neuroendocrine Tumors Measuring 5-9 mm: A Prospective Single-Centre Cohort Study

Study objectives:

Primary objective:

1.To determine the histologic R0 resection rate of UEMR for type I gastric NETs measuring 5-9 mm.

Secondary objectives:

To evaluate:

1. En bloc resection rate 2. Immediate and delayed adverse events 3. Procedure time 4. Histologic quality of resection (deep and lateral margins) 5. Residual disease at resection scar on surveillance endoscopy oMetachronous gastric NETs during follow-up

Inclusion: Patient-level; Age ≥18 years; Fit for endoscopic therapy and sedation; Written informed consent.

Exclusion: Technically amenable to snare resection; Lesion-level; Endoscopically visible gastric neuroendocrine tumor; Size 5-9 mm (endoscopic estimation); Clinical and/or histologic features consistent with type I gastric NET; No endoscopic features suggestive of deep invasion.

ClinicalTrials.gov NCT07728292