Switching From Sleeve Gastrectomy to Intestinal Transit Bipartition Surgery in Adults With Obesity
Studies how stomach emptying changes after revision surgery in adults who had sleeve gastrectomy.
Plain-language title generated from the registry record
Registry title: Transit Bipartition After Sleeve Gastrectomy
Key facts
- Where
- Ribeirão Preto, BrazilSee the site
Where in Brazil
- Hospital das Clínicas de Ribeirão PretoRibeirão Preto, BrazilNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital das Clínicas de Ribeirão Preto
- Trial code
- NCT07728682
- Record updated
- 3 August 2026
- Original description
This prospective, single-center study will evaluate adults undergoing revisional conversion from sleeve gastrectomy to intestinal transit bipartition. Forty participants will complete clinical, endoscopic, physiological, metabolic, hormonal, imaging, and stool assessments before surgery and during follow-up. The primary outcome is the within-participant change in solid-meal gastric emptying half-time (T½), measured by standardized scintigraphy from baseline to 6 months. Secondary and exploratory outcomes include reflux symptoms, DeMeester score and acid exposure, route-specific gastric transit, GLP-1 and ghrelin responses, glucose metabolism, fecal elastase, gut microbiota, body-weight trajectory, comorbidities, gastroileal anastomotic caliber, and safety.Read full original descriptionShow less
Clinical, Metabolic, and Physiological Evaluation of Conversion From Sleeve Gastrectomy to Intestinal Transit Bipartition
This prospective, single-center study will evaluate adults undergoing revisional conversion from sleeve gastrectomy to intestinal transit bipartition. Forty participants will complete clinical, endoscopic, physiological, metabolic, hormonal, imaging, and stool assessments before surgery and during follow-up. The primary outcome is the within-participant change in solid-meal gastric emptying half-time (T½), measured by standardized scintigraphy from baseline to 6 months. Secondary and exploratory outcomes include reflux symptoms, DeMeester score and acid exposure, route-specific gastric transit, GLP-1 and ghrelin responses, glucose metabolism, fecal elastase, gut microbiota, body-weight trajectory, comorbidities, gastroileal anastomotic caliber, and safety.
Inclusion: Age 18 years or older; Previous sleeve gastrectomy for the treatment of obesity; Follow-up at the HCRP gastrosurgery/bariatric surgery outpatient clinic through 2026; Clinical evaluation supporting revisional conversion to intestinal transit bipartition; Willingness to undergo the new surgical procedure and provide written informed consent.
Exclusion: Absence of willingness to undergo a new surgical procedure; Liver cirrhosis.