Two airway clearing methods compared in children with cystic fibrosis
Compares two ways of clearing the airways in children with cystic fibrosis.
Plain-language title generated from the registry record
Registry title: Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
Key facts
- Where
- Multan Khurd, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 12 years old?
Source: NCT07729787, who can take part
Where in Pakistan
- Nishter Hospital MultanMultan Khurd, PakistanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Riphah International University
- Trial code
- NCT07729787
- Record updated
- 28 July 2026
- Original description
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.Read full original descriptionShow less
Comparative Effects of Autogenic Drainage and Mechanical Percussion on Lung Function, Dyspnea and Quality of Life in Children With Cystic Fibrosis
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.
The main questions it aims to answer are:
* Does autogenic drainage improve lung function more effectively than mechanical percussion in children with cystic fibrosis? * Does autogenic drainage reduce dyspnea (breathlessness) more effectively than mechanical percussion? * Does autogenic drainage improve health-related quality of life more effectively than mechanical percussion?
Researchers will compare autogenic drainage with mechanical percussion to determine which airway clearance technique provides greater benefits for children with cystic fibrosis.
Participants will:
* Be randomly assigned to receive either autogenic drainage or mechanical percussion therapy. * Participate in supervised treatment sessions five times per week for six weeks. * Undergo assessments of lung function using spirometry (FEV₁ and FVC), dyspnea using the Modified Borg Dyspnea Scale, and quality of life using the Cystic Fibrosis Questionnaire-Revised (CFQ-R) before and after the intervention period.
The findings of this study may help identify the most effective airway clearance technique for improving respiratory health and quality of life in children with cystic fibrosis.
Inclusion: Confirmed diagnosis of cystic fibrosis (CF) through a sweat test or genetic testing; Age between 6 and 12 years; Clinically stable condition (no acute pulmonary exacerbation within the last 4 weeks).
Exclusion: History of thoracic surgery; Active hemoptysis; Severe physical or cognitive disabilities limiting participation in the intervention or assessments.