Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband
Key facts
- Who runs it
- Yeditepe University Hospital
- Where
- Istanbul, TürkiyeSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 40 people, planned
- Started
- 22 Jul 2026
- Expected to end
- 1 Feb 2027
- Type of study
- Interventional
- Treatments tested
- Xiomi Smart Band 10
- Record updated
- 25 September 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Age 18 years or older
- Undergoing total thyroidectomy at the Department of General Surgery, Yeditepe University Faculty of Medicine Hospital
- Initiation of postoperative levothyroxine replacement therapy as part of routine clinical care
- Willing and able to attend the routine 1-month postoperative thyroid function test follow-up
- Willing and able to wear the Xiaomi Smart Band 10 throughout the study period
- Able to provide written informed consent
Who cannot take part
- History of cardiac arrhythmia
- Current use of beta-blockers or other antiarrhythmic medications that may affect heart rate
- History of heart failure or advanced cardiovascular disease
- Diagnosed sleep disorders that may interfere with nighttime heart rate measurements
- Missing clinical or laboratory data required for outcome assessment
- Pregnancy
- Inability or unwillingness to wear the Xiaomi Smart Band 10 as required
- Refusal to participate or withdrawal of informed consent
Where in Türkiye
- Yeditepe University Kosuyolu HospitalIstanbul, TürkiyeContact: Banu Erkal, MDTaking people
About the trial
What the trial wants to find out
The goal of this observational study is to determine whether nighttime heart rate and heart rhythm data collected by a smart wristband can identify under- or over-replacement with levothyroxine before the routine 1-month thyroid function tests in adults who have undergone total thyroidectomy.
Read full original descriptionShow less
After total thyroidectomy, patients usually start levothyroxine replacement therapy, and the dose is adjusted about 1 month later based on thyroid function tests. This study aims to determine whether changes in nighttime heart rate and heart rhythm can provide an earlier indication that the levothyroxine dose is too low or too high.
The main questions it aims to answer are:
Can nighttime heart rate and heart rhythm measured by a smart wristband identify under- or over-replacement with levothyroxine before routine thyroid function testing? How well do smart wristband measurements agree with thyroid function test results?
Participants will:
Wear a smart wristband after total thyroidectomy. Continue taking levothyroxine as prescribed by their physician. Undergo routine thyroid function testing approximately 1 month after surgery as part of standard clinical care.
Allow researchers to compare smart wristband measurements with thyroid function test results to evaluate whether wearable data can provide an earlier indication of inadequate or excessive levothyroxine replacement.
The group in the trial
- Total Thyroidectomy Patients Receiving LevothyroxineTreatment being tested
Adults undergoing total thyroidectomy who receive standard postoperative levothyroxine replacement therapy. Participants will wear a smart wristband during the early postoperative period to continuously record nighttime heart rate and heart rhythm. They will undergo routine thyroid function testing, including serum thyroid-stimulating hormone (TSH) and free thyroxine (fT4), 1 month after surgery as part of standard clinical care. Smart wristband-derived physiological data will be compared with thyroid function test results to evaluate whether wearable monitoring can identify under- or over-replacement with levothyroxine before the routine 1-month biochemical assessment.
Treatment: Xiomi Smart Band 10
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Comparative Evaluation of the Effectiveness of Levothyroxine Replacement Therapy After Total Thyroidectomy Using Smart Wristband-Measured Nocturnal Heart Rate and Heart Rhythm Parameters Versus Thyroid Function Tests
- Record updated
- 25 September 2026