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Effects of IMT on Cardiopulmonary Endurance and Functional Mobility in KOA

This trial has no sites in United States.

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Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 65 years old?

Source: NCT07738627, who can take part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Riphah International University
Trial code
NCT07738627
Record updated
27 August 2026
Original description
The purpose of the study is to investigate whether adding Inspiratory Muscle Training (IMT) to the usual treatment of patients with knee osteoarthritis improves their cardiopulmonary endurance and functional mobility more than standard care alone.Read full original descriptionShow less

Inspiratory Muscle Training as an Adjunct to Standard Care: Effects on Cardiopulmonary Endurance and Functional Mobility in Knee Osteoarthritis

The purpose of the study is to investigate whether adding Inspiratory Muscle Training (IMT) to the usual treatment of patients with knee osteoarthritis improves their cardiopulmonary endurance and functional mobility more than standard care alone.

Inclusion: Age 40-65 years; Male and Female participants; Bilateral Knee Osteoarthritis; Diagnosed according to American College of Rheumatology criteria; Kellgren and Lawrence Grade II-III; Able to walk independently; Willing to provide informed consent.

Exclusion: Intra-articular corticosteroid injection within last 3 months; Lower limb trauma or surgery history; Planned surgery during study period; Severe cardiovascular disease; Severe pulmonary disease; Neurological disorders; Psychological disorders; Participation in structured physical activity programs; Hyaluronic acid injection within last 6 months.

ClinicalTrials.gov NCT07738627