An online and remote group program to ease fear of cancer progression in women
Tests an online and remote group program for fear of cancer worsening in women.
Plain-language title generated from the registry record
Registry title: A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer
Key facts
- Where
- Arcadia, Duarte, Huntington Beach, Irvine, Lancaster, Long Beach, Santa Clarita, Simi Valley, South Pasadena, Upland, and West Covina, United StatesSee the 11 sites
Where in United States
- City of Hope at ArcadiaArcadia, United StatesTaking people
- City of Hope Medical CenterDuarte, United StatesTaking people
- City of Hope at SeacliffHuntington Beach, United StatesTaking people
- City of Hope at Irvine LennarIrvine, United StatesTaking people
- City of Hope Antelope ValleyLancaster, United StatesTaking people
- City of Hope at Long Beach ElmLong Beach, United StatesTaking people
- City of Hope at Santa ClaritaSanta Clarita, United StatesTaking people
- City of Hope at Simi ValleySimi Valley, United StatesTaking people
- City of Hope at South PasadenaSouth Pasadena, United StatesTaking people
- City of Hope at UplandUpland, United StatesTaking people
- City of Hope at West CovinaWest Covina, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- City of Hope Medical Center
- Trial code
- NCT07741968
- Record updated
- 16 October 2026
- Original description
This clinical trial studies whether an intervention supported by technology (blended e-health intervention) works to improve fear of progression (FOP) in women with gynecologic or breast cancer. FOP is the fear patients experience from the possibility that their cancer could grow, spread, or get worse. Managing FOP is a leading unmet concern of cancer patients. High levels of FOP are associated with distress, depression, and increased health care costs, despite this, access to resources to address FOP remain limited. The blended e-health intervention in this trial offers remote group sessions along with online sessions to help patients access the information. Session content incorporates values-based goal setting and skills practices to manage unhelpful beliefs about worry and promote helpful coping behaviors. The sessions may help patients recognize unhelpful thoughts and behaviors which reinforce worry. A blended e-health intervention may be an effective way to improve FOP in women with gynecologic or breast cancer.Read full original descriptionShow less
An e-Health Intervention for Fear of Progression in Women With Gynecologic or Breast Cancer
This clinical trial studies whether an intervention supported by technology (blended e-health intervention) works to improve fear of progression (FOP) in women with gynecologic or breast cancer. FOP is the fear patients experience from the possibility that their cancer could grow, spread, or get worse. Managing FOP is a leading unmet concern of cancer patients. High levels of FOP are associated with distress, depression, and increased health care costs, despite this, access to resources to address FOP remain limited. The blended e-health intervention in this trial offers remote group sessions along with online sessions to help patients access the information. Session content incorporates values-based goal setting and skills practices to manage unhelpful beliefs about worry and promote helpful coping behaviors. The sessions may help patients recognize unhelpful thoughts and behaviors which reinforce worry. A blended e-health intervention may be an effective way to improve FOP in women with gynecologic or breast cancer.
Inclusion: Women with stage III or IV GYN (ovarian, endometrial, cervical, vulvar/vaginal) or breast cancer who are at least 2 months from initial diagnosis OR Women with stage I or II endometrial, ovarian, or breast cancer with carcinosarcoma histology OR Women with stage I or II triple negative breast cancer; Score ≥ 34 on the Fear of Progression Short-Form, indicating dysfunctional levels; Age 18 or older; able to read and understand English; Patients can be on active treatment or surveillance. They can be no evidence of disease (NED), recurrent or with progressive disease.
Exclusion: Ongoing uncontrolled active psychiatric condition that, in the opinion of the investigator, would interfere in the conduct of the study (e.g., mood disorders, psychosis disorders, or substance use), Major depression as assessed by Patient Health Questionnaire-9 (PHQ-9); Enrolled in hospice; Non-English speaking; Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics); Current participation in a mind-body or mindfulness education program within the past six weeks.