Following Young People at Higher Risk for Common Mental Disorders
Follows children and teens at higher risk for depression, anxiety, or obsessive-compulsive disorder over time.
Plain-language title generated from the registry record
Registry title: Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 7 and 17 years old?
Source: NCT07744490, who can take part
Where in China
- Shanghai Mental Health CenterShanghai, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai Mental Health Center
- Trial code
- NCT07744490
- Record updated
- 4 August 2026
- Original description
This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and obsessive-compulsive disorder, based on family history or subthreshold emotional or behavioral symptoms. Participants will be followed for two years. Clinical assessments, questionnaires, EEG, biological samples, and MRI will be collected at scheduled intervals. The study aims to identify factors associated with the onset and progression of these disorders and support early risk identification.Read full original descriptionShow less
A Longitudinal Study for Risk Identification of Common Mental Disorders in High-Risk Children and Adolescents
This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and obsessive-compulsive disorder, based on family history or subthreshold emotional or behavioral symptoms. Participants will be followed for two years. Clinical assessments, questionnaires, EEG, biological samples, and MRI will be collected at scheduled intervals. The study aims to identify factors associated with the onset and progression of these disorders and support early risk identification.
Inclusion: Aged 7-17 years at enrollment; Meeting at least one of the following conditions: Having at least one first-degree relative with a depressive disorder, anxiety disorder, or obsessive-compulsive disorder; or exhibiting clinically relevant but subthreshold depressive, anxiety, obsessive-compulsive, or repetitive behavioral symptoms; Not meeting the full diagnostic criteria for a depressive disorder, anxiety disorder, or obsessive-compulsive disorder at baseline, as assessed using the K-SADS-PL; Willing and able to participate in the scheduled assessments and follow-up visits; Written informed consent provided by a parent or legal guardian and assent provided by the participant.
Exclusion: A current or previous diagnosis of a depressive disorder, anxiety disorder, or obsessive-compulsive disorder; A severe psychiatric condition requiring immediate clinical intervention, including acute suicide risk, a psychotic disorder, or a bipolar disorder; A major neurological disorder, severe head injury, or serious or unstable medical condition that may interfere with study participation; Intellectual or cognitive impairment that prevents the participant from understanding or completing the study assessments; Inability or unwillingness of the participant or legal guardian to comply with the study procedures.