Tests brain stimulation with exercise for thinking skills in schizophrenia
Tests brain stimulation combined with aerobic exercise in adults with schizophrenia.
Plain-language title generated from the registry record
Registry title: The Effect of Combined Brain Stimulation and Exercise for Improving Cognitive Function in Schizophrenia
Key facts
- Where
- Hung Hom, Hong KongSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07745140, who can take part
Where in Hong Kong
- The Hong Kong Polytechnic UniversityHung Hom, Hong KongNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Hong Kong Polytechnic University
- Trial code
- NCT07745140
- Record updated
- 4 August 2026
- Original description
The study will investigate the (1) additive and synergistic effects of tDCS and aerobic exercise on cognitive function and clinical symptoms in schizophrenia, and (2) neurophysiological mechanisms (mediators) underlying these effects.Read full original descriptionShow less
Feasibility of an Integrative Treatment of Brain Stimulation and Exercise on Cognitive Function in Schizophrenia: A Pilot Randomized Controlled Trial
The study will investigate the (1) additive and synergistic effects of tDCS and aerobic exercise on cognitive function and clinical symptoms in schizophrenia, and (2) neurophysiological mechanisms (mediators) underlying these effects.
Inclusion: Schizophrenia spectrum disorders; Aged from 18 to 65; Chinese-speaking (to enable cognitive testing); Ability to understand the nature of the study and to give informed consent; Fewer than 10 hours of physical exercise in the previous 3 months.
Exclusion: Severe physical illness (Myocardial Infarction, Hypertension, Fracture, Spinal problems in which exercise with mild-to-moderate intensity may be contraindicated); Comorbid diagnoses of organic brain syndrome, substance misuse, history of epilepsy or seizure, intellectual disability, significant head trauma, active suicidal ideation or self-harm behaviors; Known pregnancy, or other contraindication to tDCS or MRI (e.g., have a cardiac/heart pacemaker, brain aneurysm clips, any implanted metallic or electrical device, or any internal metal foreign objects).