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Comparing Two Nerve Blocks for Pain Relief After Lung Cancer Keyhole Surgery

Compares two nerve blocks for pain after lung cancer surgery in adults.

Key facts

Who runs it
Nanjing First Hospital, Nanjing Medical University
Where
Nanjing, ChinaSee the site
Trial code
Registry title
Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery
Status
Recruiting
People taking part
130 people, planned
Started
5 Aug 2026
Expected to end
30 May 2028
Type of study
Interventional, 2 groups
Treatments tested
  • Ultrasound-guided retro-SCTLB
  • Ultrasound-guided TPVB
Record updated
6 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults having keyhole (thoracoscopic) surgery to remove lung cancer under general anesthesia. It compares two pain-relief nerve blocks after surgery.

Age
18 to 80 years
Sex
All sexes
Disease stage
Planned thoracoscopic radical surgery for lung cancer under general anesthesia. ASA class I-III.
Earlier treatment
No history of opioid abuse.

Main reasons for not taking part

  • Allergy to the study drug or local anesthetic
  • History of opioid abuse
  • Skin infection at the needle site of ITPN or TPVB
  • Peripheral infectious neuropathy
  • Blood clotting disorder

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

  • Patients scheduled for thoracoscopic radical lung cancer surgery under general anesthesia;
  • aged 18-80 years;
  • BMI 18-30 kg/m²;
  • ASA classification I-III;

Who cannot take part

  • Allergy to the study drug or local anesthetic
  • History of opioid abuse
  • Pre-existing skin infection at the puncture site of ITPN or TPVB
  • Peripheral infectious neuropathy
  • Dysfunction of blood coagulation

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Where in China

  • Nanjing First HospitalNanjing, ChinaContact: Tao ShanTaking people

About the trial

What the trial wants to find out

The aim of this clinical trial is to investigate the effects of postoperative analgesia during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing thoracoscopic radical resection of lung cancer。By comparing the dosage of opioid drugs after surgery, the impact of retro-SCTLB and TPVB on the postoperative analgesic effect was evaluated.

The 2 groups in the trial

  • retro-SCTLB groupTreatment being tested

    A total of 20 ml of the 0.375% ropivacaine is injected in the retro-superior costotransverse ligament space in the retro-SCTLB group。

    Treatment: Ultrasound-guided retro-SCTLB

  • TPVB groupTreatment being tested

    A total of 20 ml of the 0.375% ropivacaine is injected in the paravertebral space in the TPVB group .

    Treatment: Ultrasound-guided TPVB

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Postoperative Analgesic Effects of Ultrasound-guided Retro-superior Costotransverse Ligament Space Block After Video-assisted Thoracoscopic Surgery: a Prospective Randomized Controlled Trial
Plain-language title
Comparing Two Nerve Blocks for Pain Relief After Lung Cancer Keyhole SurgeryGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Fit questions
Built from NCT07745881, who can take part
Record updated
6 August 2026