NCT07745920Recruiting
Managing Depressive Symptoms in ADPKD
A Pilot Study for Managing Depressive Symptoms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 105 (estimated)
- First submitted
- 30 Jul 2026
- Start date
- 12 Jun 2026
- Primary completion date
- 12 Jul 2027
- Lead sponsor
- Mayo Clinic
- Diseases
- Polycystic kidney disease
- NCT number
- NCT07745920
What you commit to
- Study type: Interventional
- Planned participants: 105
- From 12 Jun 2026 to the primary completion date, 12 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Anticipated dialysis or transplant within 6 months
- Prior chronic dialysis
- Prior organ (liver or kidney) transplant
Other illness
- Suicidal ideation/unstable mental illness of any kind
- Significant cognitive impairment (Mini Mental Status Exam (MMSE))
Lab values
- eGFR \<10 ml/min/1.73m2
Other
- Lack of access/ability to use internet-based programs
- Lack of English language fluency
Who the study is looking for
- Confirmed clinical diagnosis of ADPKD using Pei-Ravine criteria
- Pre-End Stage Kidney Disease, with Stage 1-5 CKD (eGFR \>10 ml/min/1.73m2, with no anticipated dialysis or transplant within 12 months)
- Clinical or self-diagnosis of depression
- English-language fluency
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.