Two Anesthetic Gas Approaches and Time to Breathing Tube Removal in Weight-Loss Surgery
Compares two anesthetic gas plans on waking time in adults having bariatric surgery.
Plain-language title generated from the registry record
Registry title: Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
Key facts
- Where
- Santiago, ChileSee the site
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having planned keyhole (laparoscopic) gastric bypass surgery for obesity. It compares two ways of giving anesthetic gas.
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Planned laparoscopic gastric bypass surgery; body mass index between 30 and 50 kg/m²; American Society of Anesthesiologists physical status II or III
Main reasons for not taking part
- Surgery lasting less than 2 hours
- Body mass index greater than 50 kg/m²
- Significant heart disease
- Moderate or severe obstructive lung disease, including uncontrolled asthma or COPD
- Pregnancy or breastfeeding
Read by machine on 12 November 2026.
Where in Chile
- Clínica DávilaSantiago, ChileContact: Alejandra Alejandra Rivera, MsC EpidemiologyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Clínica Dávila
- Trial code
- NCT07748247
- Record updated
- 5 August 2026
- Original description
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.Read full original descriptionShow less
Desflurane Versus Sevoflurane-Desflurane Swap in Adults Undergoing Bariatric Surgery: A Randomized Non-Inferiority Trial on Extubation Time
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.
Inclusion: Age 18 years or older; Scheduled for elective laparoscopic gastric bypass surgery; Body mass index between 30 and 50 kg/m²; American Society of Anesthesiologists physical status II or III; Able and willing to provide written informed consent.
Exclusion: Surgical procedure lasting less than 2 hours; Active illicit drug use or substance dependence; Significant cardiac disease; Moderate or severe obstructive respiratory disease, including uncontrolled asthma or chronic obstructive pulmonary disease; Known allergy or contraindication to medications used during the intraoperative period; Personal or family history of malignant hyperthermia; Advanced chronic kidney disease, defined as an estimated glomerular filtration rate below 60 mL/min; Myasthenia gravis or another neuromuscular junction disorder; Severe cognitive or psychiatric disorder; Body mass index greater than 50 kg/m²; Pregnancy or breastfeeding; Refusal to participate or withdrawal of informed consent at any time.