Brain Signals, Walking Freezes and Balance Problems in Parkinson's Disease
Studies how brain signals and deep brain stimulation settings relate to walking and balance problems.
Plain-language title generated from the registry record
Registry title: Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
Key facts
- Where
- Cleveland, United StatesSee the site
Where in United States
- Cleveland ClinicCleveland, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Cleveland Clinic
- Trial code
- NCT07748962
- Record updated
- 26 October 2026
- Original description
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these symptoms.Read full original descriptionShow less
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these symptoms.
Inclusion: You have been diagnosed with Parkinson's disease; You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device; Your DBS settings have been stable for at least 3 months; You experience freezing of gait (sudden inability to move your feet when trying to walk); You are able to walk on your own for at least 10 minutes without assistance; You are willing to temporarily stop your Parkinson's medications and have your DBS settings adjusted for study testing; You are able to understand the study and provide consent to participate.
Exclusion: You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis); You have been diagnosed with dementia or have difficulty understanding the study or giving consent; You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate; You currently have alcohol or substance abuse problems; You have hearing or vision problems that would make it difficult to use a virtual reality headset.