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Building a safe, personalized exercise program for people who have finished cancer treatment

Develops personalized exercise plans for adults who completed cancer treatment at least 2 months ago.

Key facts

Who runs it
Kaohsiung Medical University Chung-Ho Memorial Hospital
Where
Kaohsiung, TaiwanSee the site
Trial code
Registry title
Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations
Status
Recruiting
People taking part
150 people, planned
Started
12 Mar 2026
Expected to end
31 Aug 2027
Type of study
Interventional
Treatments tested
  • structured exercise training
Record updated
7 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 18 to 80 who finished treatment for stage I-III cancer at least 2 months ago and do not exercise enough. It tests a personalized exercise plan.

Age
18 to 80 years
Sex
All sexes
Disease stage
Cancer confirmed by tissue tests, AJCC TNM stage I-III, with ECOG performance status 0-2.
Earlier treatment
Must have finished treatment meant to remove all of the disease (surgery with or without chemotherapy or radiotherapy) at least 2 months ago. Must not be in another formal exercise or weight-loss program.

Main reasons for not taking part

  • Heart problems in the past 3 months, such as heart attack, unstable angina, uncontrolled arrhythmia, or resting blood pressure above 180/110 mmHg
  • Resting oxygen saturation below 90%
  • Unstable bone metastasis or high risk of bone fracture, or a recent major fracture or orthopedic surgery
  • Low platelets (below 50,000/μL), severe anemia (Hb below 8 g/dL), or low neutrophils (below 1,000/μL)
  • Doctor or investigator judges that exercise is not safe for the person

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • Aged 18 to 80 years
  • Cancer Cohorts: Pathologically confirmed diagnosis of AJCC TNM stage I-III, and having completed curative-intent treatment (including surgery ± adjuvant chemotherapy/radiotherapy, etc) for at least 2 months
  • Cancer cohort must have an Eastern Cooperative Oncology Group (ECOG) Performance Status score of 0-2
  • Ability to comply with weekly structured exercise training (3-4 professionally supervised sessions per week) and willingness to accept telephone follow-ups or report exercise status via exercise logs/wearable devices
  • Self-reported failure to meet the following physical activity guidelines within the past 3 months: at least 150 minutes of moderate-intensity aerobic exercise per week OR at least 75 minutes of vigorous-intensity aerobic exercise per week; AND no regular resistance training (≥ 2 sessions per week) within the past 3 months

Who cannot take part

  • Concurrent participation in other formal exercise or weight-loss intervention programs
  • Cardiovascular instability: History of acute coronary syndrome (ACS), myocardial infarction (MI), acute exacerbation of heart failure, or hospitalization for heart failure within the past 3 months; unstable angina; uncontrolled arrhythmia; or uncontrolled hypertension (resting blood pressure > 180/110 mmHg)
  • Musculoskeletal or neurological risks: Unstable bone metastasis or bone metastasis with a high risk of fracture; recent major fracture or orthopedic surgery where weight-bearing is not yet permitted; or other severe neuromuscular diseases that compromise the safety of exercise
  • Hematological risks: Thrombocytopenia (Platelet count < 50,000/μL), severe anemia (Hemoglobin [Hb] < 8 g/dL), or neutropenia (Absolute Neutrophil Count [ANC] < 1,000/μL)
  • Hypoxemia: Resting oxygen saturation (SpO2) < 90%
  • Metabolic instability: Severe hypoglycemic event or diabetic ketoacidosis (DKA) within the past 3 months
  • Deemed unsuitable for exercise intervention as determined by clinical assessment from the attending physician or study investigator
  • Inability to comprehend or complete the informed consent form, or inability to comply with the study procedures

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Where in Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial HospitalKaohsiung, TaiwanContact: Ko-Long Lin, PhDTaking people

About the trial

What the trial wants to find out

The purpose of this study is to establish a safe and systematic exercise assessment and prescription program for cancer survivors. It can be challenging for cancer patients to start exercising due to various health risks, so this study aims to create a personalized and easily reproducible workflow. The study will include cancer patients who have completed their primary curative treatments at least 2 months ago.

Read full original descriptionShow less

Participants will undergo a comprehensive health and fitness evaluation led by a study physician. This evaluation includes:

* A review of medical history and cardiovascular risk. * Functional physical fitness tests. * Cardiopulmonary Exercise Testing (CPET) to carefully evaluate heart and lung function during physical exertion. * A musculoskeletal ultrasound, if deemed necessary. Based on these combined results, the medical team will determine each participant's exercise risk level and design a personalized exercise prescription. Participants will then be assigned to an appropriate and safe exercise setting.

To ensure safety and maximize health benefits, the study includes a continuous tracking system. Participants will report their exercise progress every 4 weeks and undergo a full reassessment every 3 months. The medical team will use this feedback to safely adjust the participant's risk level and exercise prescription over time.

The group in the trial

  • Experimental groupTreatment being tested

    structured exercise intervention group

    Treatment: structured exercise training

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
A Program for the Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations
Plain-language title
Building a safe, personalized exercise program for people who have finished cancer treatmentGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT07751783, who can take part
Record updated
7 August 2026