Mediterranean diet and limited eating hours for people with ulcerative colitis in remission
Compares diet changes for gut health in adults with ulcerative colitis in remission.
Plain-language title generated from the registry record
Registry title: Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission
Key facts
- Where
- Santiago, ChileSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07752446, who can take part
Where in Chile
- Pontificia Universidad Catolica de ChileSantiago, ChileTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Pontificia Universidad Catolica de Chile
- Trial code
- NCT07752446
- Record updated
- 7 August 2026
- Original description
This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission.Read full original descriptionShow less
Mediterranean Diet and Time-Restricted Feeding Intervention to Improve Gut Health, Quality of Life and Inflammation in Patients With Ulcerative Colitis in Remission: A Pilot Randomized Controlled Trial
This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission.
Participants will be randomly assigned to one of three groups: a Mediterranean diet, a Mediterranean diet combined with time-restricted feeding (eating within an 8-hour window each day), or standard dietary advice. The Mediterranean diet emphasizes fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting processed foods and red meat.
The main outcome will be changes in short-chain fatty acids in stool samples, which are markers of gut health. Additional outcomes include changes in inflammation markers, gastrointestinal symptoms, and quality of life.
The results of this study may help identify effective dietary strategies to support patients with ulcerative colitis.
Inclusion: Adults aged 18 to 60 years; Diagnosis of ulcerative colitis; Clinical remission for at least 6 months; Fecal calprotectin < 250 µg/g in the last 3 months; Daily eating window ≥ 11 hours.
Exclusion: History of gastrointestinal surgery; Liver or kidney disease; Eating disorders; Active ulcerative colitis; Pregnancy; Use of supplements (protein, antioxidants, probiotics); Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP); High levels of physical activity.