Stigma feelings and quality of life in men with low testosterone
Compares stigma and illness views in men with hypogonadism and other endocrine diseases.
Key facts
- Who runs it
- Hacettepe University
- Where
- Bingoel and Malatya, TürkiyeSee the 2 sites
- Trial code
- Registry title
- Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism
- Status
- Recruiting
- People taking part
- 90 people, planned
- Started
- 20 Oct 2026
- Expected to end
- 30 Oct 2027
- Type of study
- Observational, 2 groups
- Record updated
- 6 November 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for men aged 18 or older. One group has hypogonadism (low testosterone). The other group has diabetes, high blood pressure or an underactive thyroid.
- Age
- 18 years or older
- Sex
- Men only
- Disease stage
- Hypogonadism group: total testosterone below 300 ng/dL with at least one symptom. Comparison group: diabetes, hypertension or hypothyroidism with regular endocrinology follow-up and total testosterone of 300 ng/dL or more.
- Biomarker or test result
- Total testosterone below 300 ng/dL (hypogonadism group) or 300 ng/dL or more (comparison group)
Main reasons for not taking part
- Active psychiatric diagnosis such as active psychosis or bipolar disorder
- Chronic inflammatory or rheumatological disease affecting body composition
- Uncontrolled other endocrine disease or severe complications (for example HbA1c above 8.0% (64 mmol/mol))
- Cognitive impairment or dementia, or limited literacy that prevents completing the questionnaires
- Klinefelter syndrome
The registry criteria, word for word
Show all 19 criteriaShow less
Who can take part
- Cases:
- Male, aged 18 years or older
- Biochemically confirmed hypogonadism (total testosterone < 300 ng/dL with at least one clinical symptom)
- Regular follow-up at the endocrinology outpatient clinic
- Fluent in reading and understanding Turkish
- Signed informed consent; Controls:
- Male, aged 18 years or older
- Diagnosed with diabetes, hypertension, or hypothyroidism under regular endocrinology follow-up
- Total testosterone ≥ 300 ng/dL
- Age-matched to a participant in the case group (±5 years)
- Fluent in reading and understanding Turkish
- Signed informed consent
Who cannot take part
- Active psychiatric diagnosis (e.g., active psychosis, bipolar disorder)
- Chronic inflammatory or rheumatological diseases affecting body composition (e.g., chronic kidney disease, IBD, rheumatoid arthritis, SLE, ankylosing spondylitis)
- Cognitive impairment or dementia precluding questionnaire completion
- Klinefelter syndrome
- Uncontrolled co-existing endocrine conditions or severe complications (e.g., HbA1c > 8.0%, diabetic neuropathy/nephropathy/retinopathy, non-euthyroid state)
- Literacy limitations preventing completion of self-report measures
- Additional control exclusion: Diagnosis or clinical suspicion of hypogonadism
Where in Türkiye
- Bingöl University Faculty of Physical Therapy and RehabilitationBingoel, TürkiyeContact: Aybüke Fanuscu, Pt, PhDTaking people
- Malatya Training and Research HospitalMalatya, TürkiyeContact: Emine Şener Aydın, MDTaking people
About the trial
What the trial wants to find out
This study aims to systematically compare the levels of anticipated illness stigma and illness identity among men diagnosed with hypogonadism to those of men with other chronic endocrine conditions (e.g., diabetes mellitus, hypothyroidism, and hypertension). Furthermore, it examines whether these psychosocial variables predict quality-of-life deterioration specifically within the hypogonadism cohort.
The 2 groups in the trial
- Hypogonadism Group (Case)
Male patients aged 18 years or older with biochemically confirmed hypogonadism (total testosterone \< 300 ng/dL with at least one clinical symptom) undergoing regular follow-up in the endocrinology clinic.
- Control Group (Other Chronic Endocrine Diseases)
Male patients aged 18 years or older diagnosed with diabetes mellitus, hypertension, or hypothyroidism without hypogonadism (total testosterone ≥ 300 ng/dL), matched by age (±5 years) to the case group and under regular follow-up in the same endocrinology clinic.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Impact of Anticipated Illness Stigma and Illness Identity on Quality of Life in Men With Hypogonadism: A Comparative Study With Other Chronic Endocrine Diseases
- Plain-language title
- Stigma feelings and quality of life in men with low testosteroneGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 13 November 2026.
- Record updated
- 6 November 2026