Building a Diagnostic Rule for Acute Heart Failure in Emergency Departments

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who come to the emergency department with suspected acute heart failure or sudden shortness of breath. It tests a combined way to diagnose acute heart failure.

Age

18 years and older

Sex

All sexes can join.

Disease stage

Suspected acute heart failure or acute shortness of breath (dyspnea). Symptoms include shortness of breath, swollen legs, difficulty breathing when lying flat, waking at night short of breath, breathlessness on exertion, or weight gain.

Main reasons for not taking part

• Trauma patients
• Pregnancy
• Unstable patients who need invasive airway treatment
• Patients who refuse to take part

The registry criteria, word for word

What the trial wants to find out

The goal of this prospective observational cohort study is to establish a comprehensive clinical prediction rule integrating clinical characteristics, point-of-care testing (POCT) of NT-proBNP, an 8-point LUS, and a rapid cardiac assessment using bedside echocardiography for diagnosing acute heart failure (AHF) in the emergency department. A clinical prediction rule with high diagnostic accuracy will minimize delays and misdiagnoses, as well as the potential harm they may cause to patients. The primary outcome measure is the adjudicated AHF diagnosis. Secondary outcome measures include ED and discharge diagnosis of the patients.

The 2 groups in the trial

• Testing Cohort

  Patients from PWH and TMH

  Treatment: Acute Heart Failure Diagnostic Method

• Validation Cohort

  Patients from QMH

  Treatment: Acute Heart Failure Diagnostic Method