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Quality of life during immunotherapy after chemoradiotherapy for locally advanced lung cancer

Follows how adults with locally advanced lung cancer feel during immunotherapy.

Plain-language title generated from the registry record
Registry title: Aspects of Quality of Life During Adjuvant Oncological Treatment for Locally Advanced Lung Cancer Which Include Immune Checkpoint Inhibitor.

Key facts

Where
Gothenburg, SwedenSee the site

Where in Sweden

  • Department of Oncology, Sahlgrenska University HospitalGothenburg, SwedenTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Göteborg University
Trial code
NCT07754409
Record updated
2 September 2026
Original description
Current oncological treatment for patients with locally advanced lung cancer comprise adjuvant immunotherapy (immune checkpoint inhibitors-ICI) as an additional one-year treatment after chemoradiotherapy which increases overall survival and progression-free survival. Patients with lung cancer have a high burden of distressful symptoms at diagnosis and during chemoradiotherapy. Side-effects from immunotherapy differs, they are unspecific and may develop at any point during treatment. However, it is not investigated thoroughly during adjuvant treatment in locally advanced lung cancer. As new oncological treatments are being introduced, focus must be placed on patients quality of life and how patients endure treatment to be able to know how to best support patients during this treatment. The knowledge gained from this project include how adjuvant immunotherapy treatment impacts health. This knowledge is sparse due to the novelty of the treatment.Read full original descriptionShow less

Self-reported Health During Adjuvant Immunotherapy for Locally Advanced Lung Cancer - the ImmLungCare Project.

Current oncological treatment for patients with locally advanced lung cancer comprise adjuvant immunotherapy (immune checkpoint inhibitors-ICI) as an additional one-year treatment after chemoradiotherapy which increases overall survival and progression-free survival. Patients with lung cancer have a high burden of distressful symptoms at diagnosis and during chemoradiotherapy. Side-effects from immunotherapy differs, they are unspecific and may develop at any point during treatment. However, it is not investigated thoroughly during adjuvant treatment in locally advanced lung cancer. As new oncological treatments are being introduced, focus must be placed on patients quality of life and how patients endure treatment to be able to know how to best support patients during this treatment. The knowledge gained from this project include how adjuvant immunotherapy treatment impacts health. This knowledge is sparse due to the novelty of the treatment.

Inclusion: Patients with locally advanced non-small lung cancer; cared for at either one of two specialized oncology centres; ≥ 18 years of age; planned for concurrent chemoradiotherapy including ICI for 12 months; performance status 0-2.

Exclusion: diseases or comorbidities that may have significant impact on the outcome variables; limited understanding of the Swedish language preventing the possibility to give oral and written informed consent.

ClinicalTrials.gov NCT07754409