Blood Fat Profiles and Atrial Fibrillation in a Study
Studies whether blood fat and ceramide patterns are linked to atrial fibrillation in adults.
Plain-language title generated from the registry record
Registry title: Peripheral Blood Lipidomic and Ceramide Profiles in Atrial Fibrillation
Key facts
- Where
- Xi'an, ChinaSee the site
Where in China
- First Affiliated Hospital of Xian JiaotongUniversityXi'an, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- First Affiliated Hospital Xi'an Jiaotong University
- Trial code
- NCT07757282
- Record updated
- 11 August 2026
- Original description
This prospective multi-cohort observational study evaluates the association between peripheral blood lipidomic and ceramide profiles and atrial fibrillation. The study hypothesis is that peripheral blood lipidomic features and ceramide-related profiles are associated with the presence of atrial fibrillation. Participants with atrial fibrillation and control participants with other cardiovascular diseases will be prospectively enrolled. Peripheral blood samples will be analyzed using untargeted lipidomic profiling in one cohort and targeted ceramide assays in another cohort.Read full original descriptionShow less
Association of Peripheral Blood Lipidomic and Ceramide Profiles With Atrial Fibrillation: A Prospective Multi-Cohort Observational Study
This prospective multi-cohort observational study evaluates the association between peripheral blood lipidomic and ceramide profiles and atrial fibrillation. The study hypothesis is that peripheral blood lipidomic features and ceramide-related profiles are associated with the presence of atrial fibrillation. Participants with atrial fibrillation and control participants with other cardiovascular diseases will be prospectively enrolled. Peripheral blood samples will be analyzed using untargeted lipidomic profiling in one cohort and targeted ceramide assays in another cohort.
Inclusion: Adults aged 18 years or older; Participants who are able to provide informed consent; Participants diagnosed with atrial fibrillation based on Holter monitoring, or control participants with other cardiovascular diseases and no documented atrial fibrillation; Participants with available peripheral blood samples for untargeted lipidomic profiling or targeted ceramide analysis.
Exclusion: Inability or unwillingness to provide informed consent; Missing key clinical information; Missing or poor-quality peripheral blood samples unsuitable for lipidomic or targeted ceramide analysis; Participants considered unsuitable for this study by the investigators.