Under construction – not a live service
Sign in
Not yet taking people in ItalyNo phase

Building 3D lab models from patient blood to study B-cell blood cancers

Uses extra blood from adults with CLL, splenic marginal zone lymphoma or hairy cell leukemia.

Plain-language title generated from the registry record
Registry title: Innovative 3D Preclinical Models for Mature B-cell Malignancies to Advance Personalized Immuno and Combination Therapies

Key facts

Where
Milan, ItalySee the site

Where in Italy

  • IRCCS Ospedale San RaffaeleMilan, ItalyNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
IRCCS San Raffaele
Trial code
NCT07759661
Record updated
13 August 2026
Original description
Adult patients with chronic lymphocytic leukemia (CLL), splenic marginal-zone lymphoma (SMZL) and hairy cell leukemia (HCL) followed at participating clinical sites will be enrolled and undergo sampling of additional amount of blood during the blood draws performed as part of standard clinical care.Read full original descriptionShow less

Innovative 3D Preclinical Models for Mature B-cell Malignancies to Advance Personalized Immuno and Combination Therapies

Adult patients with chronic lymphocytic leukemia (CLL), splenic marginal-zone lymphoma (SMZL) and hairy cell leukemia (HCL) followed at participating clinical sites will be enrolled and undergo sampling of additional amount of blood during the blood draws performed as part of standard clinical care.

The project aims to develop and validate innovative patient-derived 3D bioprinted models that faithfully reproduce the key microenvironments of lymphoid tissues, enabling a more physiologically relevant study of mature B-cell malignancies.

Inclusion: Age ≥18 years; Diagnosis of CLL, SMZL or HCL; Participant is willing and able to autonomously give informed consent for participation in the study.

Exclusion: Participant is unable or unwilling to provide informed consent for participation in the study.

ClinicalTrials.gov NCT07759661