Muscle loss in people hospitalized with an ischemic stroke and how they recover
Examines sarcopenia in adults with acute ischemic stroke and their recovery afterward.
Plain-language title generated from the registry record
Registry title: Sarcopenia in Acute Ischemic Stroke
Key facts
- Where
- Moscow, RussiaSee the site
Where in Russia
- Moscow State Budgetary Healthcare Institution "Moscow City Hospital named after S.S. Yudin, Moscow Healthcare Department"Moscow, RussiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)
- Trial code
- NCT07764172
- Record updated
- 22 October 2026
- Original description
The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental verification and functional-cognitive assessments, and to evaluate its impact on functional outcome at three months. The main research question is:Read full original descriptionShow less
Sarcopenia in Patients During the Acute Phase of Ischemic Stroke: Multimodal Assessment and Three-Month Functional Outcomes
The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental verification and functional-cognitive assessments, and to evaluate its impact on functional outcome at three months. The main research question is:
Is the presence of sarcopenia at admission associated with less favorable stroke outcomes, including higher rates of complications and mortality?
Participants receiving standard medical care for acute ischemic stroke will undergo extended functional assessment for sarcopenia, and a subset will additionally undergo cognitive evaluation.
Inclusion: Age 50 years and older; Acute ischemic stroke confirmed by CT or MRI; Admission within the first 72 hours; Written informed consent and availability of a contact telephone number for follow-up.
Exclusion: Active cancer at stage IV or life expectancy of less than 3 months; Neuromuscular diseases; chronic use of systemic glucocorticoids for more than 3 months; TIA without a visible lesion on neuroimaging; bilateral hemiparesis; Amputations or severe contractures that preclude anthropometric assessment; Pregnancy; refusal to participate; Discontinuation criteria (drop-out); Discharge or death within the first 7 days; Withdrawal of consent; Transfer to another facility resulting in loss of contact.