Registry of QFR-guided heart artery procedures in people with coronary artery disease
Follows adults with coronary artery disease to study QFR use in heart procedures.
Plain-language title generated from the registry record
Registry title: A Prospective Multicenter Real-World Registry of Quantitative Flow Ratio-Guided Coronary REvascularization and QuAlity evaLuation
Key facts
- Where
- Beijing, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The registry is looking for adults with coronary artery disease. Coronary angiography must show at least one main branch artery narrowed by 50% or more. They have PCI or conservative treatment.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Acute coronary syndrome (unstable angina, non-ST-segment elevation myocardial infarction, or ST-segment elevation myocardial infarction more than 4 weeks after onset) or chronic coronary syndrome (stable angina or asymptomatic myocardial ischemia). Angiography shows at least one main branch coronary stenosis of 50% or more.
- Earlier treatment
- People who have had coronary artery bypass grafting (CABG), or who plan it within 6 months, cannot join.
Main reasons for not taking part
- ST-segment elevation myocardial infarction within 4 weeks of onset
- History of CABG or planned CABG within 6 months
- Cannot undergo coronary angiography
- Non-cardiac cause with expected survival under 1 year
- Conditions that may interfere with follow-up, such as dementia or substance abuse
Read by machine on 12 November 2026.
Where in China
- National Clinical Research Center of Cardiovascular Diseases, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, ChinaContact: Fuwai hospitalTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- China National Center for Cardiovascular Diseases
- Trial code
- NCT07766434
- Record updated
- 24 September 2026
- Original description
This prospective, multicenter observational registry aims to establish a QFR-based quality control standard system for coronary revascularization in patients with coronary artery disease. The study will enroll over 10,000 patients with visually estimated at least one main branch coronary stenosis ≥50% from more than 50 centers across China (covering provincial, municipal, and county-level hospitals). Coronary angiographic images and intracoronary imaging (if available) will be collected and retrospectively analyzed by an independent core laboratory. The primary endpoint is QFR acquisition accessibility, defined as the mean of QFR usage proportion across centers.Read full original descriptionShow less
A Prospective Multicenter Real-World Registry of Quantitative Flow Ratio-Guided Coronary REvascularization and QuAlity evaLuation
This prospective, multicenter observational registry aims to establish a QFR-based quality control standard system for coronary revascularization in patients with coronary artery disease. The study will enroll over 10,000 patients with visually estimated at least one main branch coronary stenosis ≥50% from more than 50 centers across China (covering provincial, municipal, and county-level hospitals). Coronary angiographic images and intracoronary imaging (if available) will be collected and retrospectively analyzed by an independent core laboratory. The primary endpoint is QFR acquisition accessibility, defined as the mean of QFR usage proportion across centers.
Inclusion: Age ≥18 years; Coronary angiography showing visually estimated at least one main branch coronary stenosis ≥50% in patients with acute coronary syndrome (including unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction >4 weeks after onset) or chronic coronary syndrome (including stable angina and asymptomatic myocardial ischemia) who undergo PCI or receive conservative treatment; Ability to understand the study design and provide written informed consent.
Exclusion: ST-segment elevation myocardial infarction within 4 weeks of onset; History of coronary artery bypass grafting (CABG) or planned CABG within 6 months; Non-cardiac cause with expected survival <1 year; Other conditions that may interfere with follow-up (e.g., dementia, substance abuse including drug addiction and other drug dependencies); Inability to undergo coronary angiography; Refusal to participate in the study.