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Electrical Stimulation Exercise for People With Lower Limb Paralysis

Tests electrical stimulation during exercise in adults with leg paralysis.

Plain-language title generated from the registry record
Registry title: Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis

Key facts

Where
Cleveland, United StatesSee the site

Where in United States

  • Louis Stokes Cleveland VA Medical CenterCleveland, United StatesTaking people

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Trial details

Who runs it
Louis Stokes VA Medical Center
Trial code
NCT07768761
Record updated
17 August 2026
Original description
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis. Specifically, surface electrical stimulation or previously implanted stimulator will be used to stimulate the muscles during various forms of exercise training with the primary focus on improving overall endurance and maximal power output. For this study, peripheral stimulating electrodes will send electrical signals to the muscles enabling the production of coordinated movements for exercise such as cycling or rowing.Read full original descriptionShow less

Efficacy of Electrical Stimulation Exercise Training for Those With Lower Limb Paralysis

The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis. Specifically, surface electrical stimulation or previously implanted stimulator will be used to stimulate the muscles during various forms of exercise training with the primary focus on improving overall endurance and maximal power output. For this study, peripheral stimulating electrodes will send electrical signals to the muscles enabling the production of coordinated movements for exercise such as cycling or rowing.

Inclusion: Lower limb paralysis due to SCI or other neurological disorder; Greater than 18 years of age; Innervated and excitable lower extremity muscles.

Exclusion: History of spontaneous fractures; Cardiovascular or pulmonary disease that would limit the ability to exercise; Uncontrolled diabetes or hypertension; Any other medical or psychological condition that would be a contraindication to participating in an exercise program; Females that are pregnant; Ventilator dependent; Current pressure injuries that would be exacerbated by exercise; Large body frame that would prevent participant from comfortably fitting the exercise equipment.

ClinicalTrials.gov NCT07768761