Brain stimulation with tACS to help arm recovery long after a stroke
Tests tACS brain stimulation for arm movement in people after stroke.
Plain-language title generated from the registry record
Registry title: tACS and Upper Limb Rehabilitation in Chronic Stroke
Key facts
- Where
- Singapore, SingaporeSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 80 years old?
Source: NCT07778342, who can take part
Where in Singapore
- Alexandra HospitalSingapore, SingaporeNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National University Hospital, Singapore
- Trial code
- NCT07778342
- Record updated
- 21 August 2026
- Original description
This study tests whether a brain stimulation technique called tACS can help stroke patients recover movement in their affected arm.Read full original descriptionShow less
Pilot Study Investigating the Neuromodulatory Effects of Transcranial Alternating Current Stimulation (tACS) on Upper Limb Motor Rehabilitation in Chronic Stroke Patients
This study tests whether a brain stimulation technique called tACS can help stroke patients recover movement in their affected arm.
Patients receive either real or fake brain stimulation three times a week for about a month (12 sessions total). During each session, they wear a cap with electrodes that deliver mild electrical currents tailored to their individual brain patterns, while researchers monitor their brain activity.
The study measures progress at three time points: before treatment, right after treatment, and one month later. Researchers use brain stimulation tests to check how well the brain controls muscles, and conduct physical tests to measure arm movement, muscle stiffness, and grip strength.
Inclusion: Age 21-80 years old; First ever stroke, at least 9 months after stroke onset; Evidence of corticomotor excitability as manifested by a recordable Motor Evoked Potential from the ipsilesional Motor Cortex (M1) by TMS measurement; Objectively documented motor weakness of the upper extremity as manifested by an Upper Extremity-Fugl-Meyer Assessment score <=55.
Exclusion: Patients with implants: cardiac, neural or medication implants; any electrically, magnetically or mechanically activated implant; brain medical devices; vascular clips or any other electrically sensitive support system in the brain; other metal implants inside the body that are contraindications of MRI scan; Patients with a history of seizures; Patients with unexplained episodes of loss of consciousness, since such condition could be related with brain alterations or epilepsy; Patients with unstable or non-controlled neuropsychiatric illness; Patients with any serious life-threatening disease such as congestive heart failure, pulmonary obstructive chronic disease or active neoplasia; Sensorimotor disturbance due to other causes other than stroke; Pregnancy; Patients with serious brain injury; Patients showing damage of skin at sites of stimulation; Patients suffering from severe or frequent headaches.