Long-term results of ab-interno trabeculotomy surgery in people with glaucoma
Follows glaucoma patients years after ab-interno trabeculotomy eye surgery.
Plain-language title generated from the registry record
Registry title: Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management
Key facts
- Where
- Würzburg, GermanySee the site
Where in Germany
- University Hospital WürzburgWürzburg, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Wuerzburg University Hospital
- Trial code
- NCT07780916
- Record updated
- 25 August 2026
- Original description
Glaucoma is one of the leading causes of irreversible vision loss worldwide. Elevated intraocular pressure (IOP) is the most important risk factor for the development and progression of the disease.Read full original descriptionShow less
Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management
Glaucoma is one of the leading causes of irreversible vision loss worldwide. Elevated intraocular pressure (IOP) is the most important risk factor for the development and progression of the disease.
Ab-interno trabeculotomy (AIT) using the Trabectome system is a minimally invasive glaucoma surgery (MIGS) that reduces aqueous humor outflow resistance by ablating the trabecular meshwork and the inner wall of Schlemm's canal, thereby lowering intraocular pressure.
Previous studies have demonstrated good short-term efficacy of this procedure. However, robust long-term data spanning several years remain scarce.
The aim of this study is to evaluate the long-term outcomes of AIT in glaucoma patients who underwent surgery between 2019 and 2021 at the Department of Ophthalmology, University Hospital Würzburg. Patients are invited for a single study visit at which intraocular pressure, visual acuity, anterior chamber angle by gonioscopy, and optic nerve structure by optical coherence tomography (OCT) are assessed. The collected data are compared with pre-operative baseline values obtained from medical records.
The results are intended to improve the assessment of long-term surgical success and to optimize patient selection for this procedure in the future.
Inclusion: Diagnosis of glaucoma; Previous ab-interno trabeculotomy (AIT) using the Trabectome device performed at the Department of Ophthalmology, University Hospital Würzburg; Surgery performed between 2019 and 2021; Ability to provide written informed consent; Age ≥ 18 years at time of surgery.
Exclusion: Inability to attend the study visit; Withdrawal of informed consent; Insufficient medical records for pre-operative baseline data retrieval.