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Online cognitive behavioural therapy and signs of response in depression and bipolar disorder

Tests online cognitive behavioural therapy in people with depression or bipolar disorder.

Plain-language title generated from the registry record
Registry title: Identifying Biomarkers of Response to Digital Interventions for Mood Disorders

Key facts

Where
Toronto, CanadaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 16 or older who have had depression or bipolar disorder and took part in an earlier CAN-BIND study. They will try online cognitive behavioural therapy (CBT).

Age
16 years or older
Sex
All sexes
Disease stage
Has met lifetime criteria for a bipolar or depressive disorder (DSM-5), assessed in a previous CAN-BIND study

Main reasons for not taking part

  • Cannot give informed consent
  • Not fluent in English
  • Does not agree to link data to the previous CAN-BIND study
  • Not willing to follow all study procedures

Read by machine on 12 November 2026.

Where in Canada

  • Centre for Addiction and Mental Health (CAMH)Toronto, CanadaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Centre for Addiction and Mental Health
Trial code
NCT07783633
Record updated
27 August 2026
Original description
The proposed study will be a single-arm pragmatic clinical trial examining the feasibility of online CBT within the CAN-BIND sites and the biomarkers of treatment response to online CBT for mood disorders.Read full original descriptionShow less

Identifying Biomarkers of Response to Digital Interventions for Mood Disorders

The proposed study will be a single-arm pragmatic clinical trial examining the feasibility of online CBT within the CAN-BIND sites and the biomarkers of treatment response to online CBT for mood disorders.

Inclusion: Must be deemed to have capacity to provide informed consent; Must sign and date the informed consent form; Stated willingness to comply with all study procedures; 16 years of age or older; Fluency in English; Meet lifetime criteria for a bipolar or depressive disorder as defined by the DSM-5 and assessed in a previous CAN-BIND study; Consent to the linkage of data to the previous CAN-BIND study.

Exclusion: Exclusion criteria for the current study include not meeting inclusion criteria only.

ClinicalTrials.gov NCT07783633