Two Nerve-Heating Procedures for Knee Osteoarthritis Pain Compared
Compares two radiofrequency ablation methods for pain from knee osteoarthritis in adults.
Plain-language title generated from the registry record
Registry title: Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain
Key facts
- Where
- Tanta, EgyptSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people over 50 with long-lasting knee osteoarthritis pain that other treatments have not helped.
- Age
- Over 50 years (minimum age 50 years).
- Sex
- Both men and women can join.
- Disease stage
- Chronic knee osteoarthritis confirmed by American College of Rheumatology criteria and plain X-ray, Kellgren-Lawrence grade II-IV, in one knee.
- Earlier treatment
- Pain not helped by other treatments such as physiotherapy, oral painkillers, and hyaluronic acid or steroid injections into the joint. No steroid or hyaluronic acid knee injection in the past 3 months. No earlier knee surgery.
Main reasons for not taking part
- Chronic knee pain caused by infection, inflammation, tumors, or fractures
- Prior knee surgery
- Acute knee pain
- Connective tissue diseases, or neurologic or psychiatric disorders
- Anticoagulant medication, local infection at the treatment site, or cognitive impairment
Read by machine on 12 November 2026.
Where in Egypt
- Tanta universityTanta, EgyptContact: Mohammed S Elsharkawy, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Tanta University
- Trial code
- NCT07789340
- Record updated
- 4 November 2026
- Original description
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.Read full original descriptionShow less
Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain: A Randomized Single-Blinded Trial
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.
Inclusion: Age > 50 years; Both genders; Diagnosed with chronic knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria and confirmed with plain radiography as the gold standard for the diagnosis of KOA; One chronic KOA pain not responding to other treatments as physiotherapy, oral analgesics, and intraarticular injection with hyaluronic acids or steroids; Kellgren-Lawrence grade (II-IV).
Exclusion: Prior knee surgery; Intra-articular knee corticosteroid or hyaluronic acids in the past 3 months; Anticoagulant medication; Chronic knee pain induced by infection, inflammation, tumors, and fractures; Connective tissue diseases; Neurologic or psychiatric disorders; Local infection of the site of intervention; Cognitive impairment; Acute knee pain.