Insomnia therapy and artery health in people with high blood pressure
Tests insomnia therapy against sleep education in adults with high blood pressure.
Plain-language title generated from the registry record
Registry title: Sleep and Arterial Function in Hypertensive Patients With Poor Sleep Quality
Key facts
- Where
- Guimarães, PortugalSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07789535, who can take part
Where in Portugal
- Unidade Local de Saúde do Alto Ave - Hospital Senhora da OliveiraGuimarães, PortugalTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Unidade Local de Saúde do Alto Ave, EPE
- Trial code
- NCT07789535
- Record updated
- 27 August 2026
- Original description
This prospective, parallel-group randomised controlled trial evaluates whether cognitive-behavioural therapy for insomnia (CBT-I) improves arterial function and psychological and cognitive outcomes in hypertensive patients with poor sleep quality. Adults aged 18-70 with controlled hypertension and poor baseline sleep quality (sleep efficiency <=85%) are randomised 1:1 to CBT-I (four weekly 60-minute sessions) or passive sleep education. The primary outcomes are change from baseline in pulse wave velocity and central arterial pressure at 12 months. Secondary outcomes include blood pressure, depressive symptoms, perceived stress, cognitive complaints, and sleep quality, assessed at baseline, 1, 6, and 12 months.Read full original descriptionShow less
Impact of Sleep on Arterial Function, Psychological and Cognitive Complaints in Hypertensive Patients With Poor Sleep Quality
This prospective, parallel-group randomised controlled trial evaluates whether cognitive-behavioural therapy for insomnia (CBT-I) improves arterial function and psychological and cognitive outcomes in hypertensive patients with poor sleep quality. Adults aged 18-70 with controlled hypertension and poor baseline sleep quality (sleep efficiency <=85%) are randomised 1:1 to CBT-I (four weekly 60-minute sessions) or passive sleep education. The primary outcomes are change from baseline in pulse wave velocity and central arterial pressure at 12 months. Secondary outcomes include blood pressure, depressive symptoms, perceived stress, cognitive complaints, and sleep quality, assessed at baseline, 1, 6, and 12 months.
Inclusion: Adults aged 18 to 70 years; Controlled hypertension; Poor baseline sleep quality (sleep efficiency <=85% assessed via actigraphy or type II polysomnography); Capable of providing informed consent; Participants with mild obstructive sleep apnea (apnea-hypopnea index 5-14.9/h on type II polysomnography) who do not meet criteria for CPAP/PAP therapy are eligible.
Exclusion: Moderate-to-severe obstructive sleep apnea (AHI >=15/h) or any obstructive sleep apnea with an indication for CPAP/PAP therapy; Severe cardiovascular disease (e.g., acute myocardial infarction or stroke); Severe neurological diseases; Central disorders of hypersomnolence; Intellectual disability; Pregnancy.