NCT07792408RecruitingPhase 1
Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives
A Phase 1, Open-label Drug Interaction Study to Evaluate the Effect of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
The purpose of the study is to evaluate the pharmacokinetic effects and safety and tolerability of VX-407 when coadministered with oral contraceptives.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 148 (estimated)
- First submitted
- 25 Aug 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 11 Mar 2027
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Diseases
- Polycystic kidney disease
- NCT number
- NCT07792408
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 148
- From 1 Sept 2026 to the primary completion date, 11 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of febrile illness within 5 days before the first dose of study drug
- Pregnant, nursing, or planning to become pregnant during the study or within 90 days after the last dose of study drug
- Other protocol defined Inclusion/Exclusion criteria will apply.
Who the study is looking for
- Body mass index (BMI) of 18.0 to 30.0 kilogram per meter square (kg/m\^2), inclusive
- A total body weight of greater than (\>) 50 kg
Age in the registry: 18 years to 50 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Altasciences - Beaumont Clinic Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.