Blood Test for Tumor DNA in High-Grade Upper Urinary Tract Cancer
Looks at tumor DNA in blood of adults having surgery for upper urinary tract cancer.
Plain-language title generated from the registry record
Registry title: Circulating Tumor DNA (ctDNA) in High Grade Upper Tract Urothelial Cancer (UTUC)
Key facts
- Where
- Baltimore, United StatesSee the site
Where in United States
- Johns Hopkins University, Sidney Kimmel Comprehensive Cancer CenterBaltimore, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Trial code
- NCT07793240
- Record updated
- 29 October 2026
- Original description
The study will evaluate the feasibility of collecting ctDNA data for UTUC patients in perioperative setting and if the data generated can help with design of future prospective trials for perioperative therapy in UTUC.Read full original descriptionShow less
Exploring the Use of Tumor Informed Circulating Tumor DNA (ctDNA) in High Grade Upper Tract Urothelial Cancer (UTUC)
The study will evaluate the feasibility of collecting ctDNA data for UTUC patients in perioperative setting and if the data generated can help with design of future prospective trials for perioperative therapy in UTUC.
Inclusion: HG UTUC patients planned for systemic therapy and or surgical intervention that will have ctDNA Signatera testing.
Exclusion: UTUC patients without high grade disease that is not planned for either systemic therapy or surgical intervention and not planned to have ctDNA Signatera testing.