Low-Intensity Endurance Exercise for Tiredness and Sleep in People With Lung Cancer
Tests gentle endurance exercise for cancer-related tiredness in adults with lung cancer.
Key facts
- Who runs it
- Taipei Medical University
- Where
- Taipei, TaiwanSee the site
- Trial code
- Registry title
- The Effects of Low-Intensity Endurance Exercise on Improving Fatigue, Sleep, Quality of Life, Mitochondrial Function, Cellular Bioelectrical Impedance Phase Angle, and Predictors of Exercise Adherence in Patients With Lung Cancer
- Status
- Recruiting
- People taking part
- 450 people, planned
- Started
- 1 Jul 2026
- Expected to end
- Jul 2029
- Type of study
- Interventional, 3 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Low-Intensity Continuous Endurance Exercise Training
- Low-Intensity Interval Endurance Exercise Training
- Record updated
- 31 August 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with lung cancer diagnosed by a physician. It tests low-intensity endurance exercise.
- Age
- 20 years or older
- Sex
- Women and men can join
- Disease stage
- Lung cancer diagnosed by a physician. The summary mentions lung cancer patients with cancer-related fatigue.
Main reasons for not taking part
- Cannot communicate in Mandarin Chinese, Taiwanese, or Hakka
- A physician finds that the person's physical condition is unsuitable for any exercise
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Individuals diagnosed with lung cancer by a physician
- Aged 20 years or older
- Education level of elementary school graduation or above
Who cannot take part
- Individuals whose physical condition is determined by a physician to be unsuitable for performing any exercise
- Individuals who are unable to communicate in Mandarin Chinese, Taiwanese, or Hakka
Where in Taiwan
- Taipei Medical UniversityTaipei, TaiwanContact: Wen-Chi Liu, MScTaking people
About the trial
What the trial wants to find out
To conduct a randomized controlled trial (RCT) targeting lung cancer patients with cancer-related fatigue to achieve the following objectives:
Read full original descriptionShow less
Objective 1: To investigate whether a low-intensity endurance exercise intervention can effectively improve mitochondrial DNA content, mitochondrial function, mitochondrial oxidative phosphorylation complex enzyme concentrations, cellular bioelectrical impedance phase angle, cancer-related fatigue, and quality of life in lung cancer patients with cancer-related fatigue.
Objective 2: To explore whether the low-intensity endurance exercise intervention improves cancer-related fatigue and quality of life in lung cancer patients through direct or indirect effects by modulating mitochondrial DNA content, mitochondrial function, mitochondrial oxidative phosphorylation complex enzyme concentrations, and cellular bioelectrical impedance phase angle.
Objective 3: To investigate the correlation between personality traits and adherence to low-intensity endurance exercise in lung cancer patients.
Objective 4: To investigate whether a low-intensity endurance exercise intervention can effectively improve sleep quality in lung cancer patients with cancer-related fatigue.
Objective 5: To investigate whether a low-intensity endurance exercise intervention can effectively reduce stress in lung cancer patients with cancer-related fatigue.
The 3 groups in the trial
- Control GroupNo study treatment, for comparison
Participants assigned to the control group will not receive any exercise intervention and will be instructed to maintain their usual daily lifestyle and physical activity throughout the study period.
- continuous exercise groupTreatment being tested
Participants will perform Level 2 low-intensity continuous endurance exercise for at least 30 consecutive minutes per day, 5 days per week. Exercise intensity will be maintained at 75-80% of peak heart rate (HRpeak), corresponding to a Rating of Perceived Exertion (RPE) of 11-12 (light). Each exercise session will consist of a 5-minute warm-up, 30 minutes of continuous low-intensity endurance exercise, and a 10-minute cool-down.
Treatment: Low-Intensity Continuous Endurance Exercise Training
- low-intensity exercise groupTreatment being tested
Participants will perform 30 minutes of interval endurance exercise per day, 5 days per week. Each session will consist of five alternating cycles, with each cycle including 3 minutes of Level 2 low-intensity endurance exercise at 75-80% HRpeak (RPE 11-12), followed by 3 minutes of Level 1 very low-intensity endurance exercise at 65-75% HRpeak (RPE \<11). Each exercise session will begin with a 5-minute warm-up and conclude with a 10-minute cool-down.
Treatment: Low-Intensity Interval Endurance Exercise Training
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Effects of Low-Intensity Endurance Exercise on Improving Fatigue, Sleep, Quality of Life, Mitochondrial Function, Cellular Bioelectrical Impedance Phase Angle, and Predictors of Exercise Adherence in Patients With Lung Cancer
- Plain-language title
- Low-Intensity Endurance Exercise for Tiredness and Sleep in People With Lung CancerGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 31 August 2026