Comparing newer breathing tests with standard spirometry to diagnose COPD and airway disease
Compares newer breathing tests with spirometry for diagnosing COPD in adults.
Plain-language title generated from the registry record
Registry title: Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
Key facts
- Where
- Andover and Southampton, United KingdomSee the 2 sites
Where in United Kingdom
- Hampshire Hospitals NHS Foundation TrustAndover, United KingdomTaking people
- University Hospital Southampton NHS Foundation TrustSouthampton, United KingdomNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Southampton NHS Foundation Trust
- Trial code
- NCT07798596
- Record updated
- 27 October 2026
- Original description
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry. However, it requires people to blow forcefully into a machine several times which can be uncomfortable and difficult for some patients.Read full original descriptionShow less
BREATHE: Benchmarking Respiratory Evaluation of Advanced Technologies for Healthcare Excellence
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry. However, it requires people to blow forcefully into a machine several times which can be uncomfortable and difficult for some patients.
This study is looking at whether newer technologies and other breathing tests can help diagnose COPD as accurately as standard testing. We will compare these tests in both hospital and community settings. We are interested in understanding how practical and cost-effective these tests are, including how easy they are to use and how comfortable they are for patients to perform.
Inclusion: ≥ 18 years of age; New referral to community or secondary healthcare services; Clinical suspicion of airway disease/COPD; Able to provide fully informed written consent; Able to fully understand and cooperate with the study protocol; Clinically stable with no contraindications to lung function testing (outlined below).
Exclusion: Recent thoracic, abdominal or eye (e.g. cataract) surgery < 6 weeks; Unstable cardiovascular status, including recent myocardial infarction or pulmonary embolus < 6 weeks; Chest infection < 6 weeks; An acute illness or symptom that might interfere with test performance (e.g. nausea, vomiting); The presence of any other clinical condition that would prevent the individual from safely performing lung function tests; Confirmed diagnosis of COPD; Not willing and/or able to provide fully informed written consent to participate; Has a relative contraindication to lung function testing [18]:; Pneumothorax < 6 weeks; Haemoptysis of unknown origin < 6 weeks; Thoracic, abdominal or cerebral aneurysm.