High-intensity interval exercise added to airway clearance for people with bronchiectasis
Tests short bursts of intense exercise plus airway clearance in adults with bronchiectasis.
Key facts
- Who runs it
- Saglik Bilimleri Universitesi
- Where
- Ankara, TürkiyeSee the site
- Trial code
- Registry title
- High-Intensity Interval Exercise in Bronchiectasis Patients
- Status
- Recruiting
- People taking part
- 42 people, planned
- Started
- 27 Mar 2026
- Expected to end
- 29 May 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- high-intensity interval exercise
- Airway clearance tecniques
- Record updated
- 4 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with stable non-cystic fibrosis bronchiectasis. It tests whether high-intensity interval exercise, added to airway clearance techniques, helps their breathing and daily life.
- Age
- Over 18 years
- Sex
- All sexes
- Disease stage
- Non-cystic fibrosis bronchiectasis, diagnosed by clinical signs and imaging. Clinically stable: no exacerbation in the last 4 weeks.
- Earlier treatment
- People who took part in a structured exercise program in the last 6 months cannot join.
- Biomarker or test result
- No gene or marker is asked for. People need no cognitive impairment (MMT>24).
Main reasons for not taking part
- Smoking
- Any other lung or airway disease besides bronchiectasis
- Heart or other conditions that make exercise unsafe, such as recent heart attack or unstable angina
- Chronic alcoholism that may affect exercise safety
- Oxygen saturation below 80% after the incremental shuttle walk test
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Being over 18 years of age
- Having a clinical and radiological diagnosis of non-cystic fibrosis bronchiectasis
- Absence of cognitive impairment (MMT>24)
- Being clinically stable (not having experienced any exacerbation in the last 4 weeks)
Who cannot take part
- Presence of any disease that may affect compliance with exercise (Unstable angina (within the last month), recent myocardial infarction (heart attack), uncontrolled arrhythmias, severe aortic stenosis, decompensated heart failure, severe pulmonary hypertension, acute respiratory tract infection, severe hypoxemia at rest (<85%), orthopedic or neurological problems that impede walking, severe anemia, acute infections, very high resting blood pressure (systolic >180-200 mmHg, diastolic >100-110 mmHg), psychological issues, etc.)
- Presence of any respiratory tract disease other than bronchiectasis
- Smoking
- Chronic alcoholism that may affect exercise safety (More than 1 drink per day on average for women, more than 2 drinks per day on average for men (1 standard drink ≈ 10-14 g of alcohol)
- After incremental shuttle walk test arterial oxygen saturation <80%
- Participation in a structured exercise program within the last 6 months
Where in Türkiye
- Gülhane Faculty of Physiotherapy and RehabilitationAnkara, TürkiyeContact: Mustafa Ertuğrul YAŞA, Associate ProfessorTaking people
About the trial
What the trial wants to find out
The aim of our study is to investigate the effect of high-intensity interval exercise (HIIE) on the symptoms of bronchiectasis in patients with the disease. The main questions it aims to answer are:
Read full original descriptionShow less
1. Does HIIE improve respiratory function in patients with bronchiectasis? 2. Does HIIE increase functional capacity, peripheral muscle strength, and quality of life in patients with bronchiectasis? 3. Does HIIE reduce the severity of dyspnea, cough symptoms, and fatigue in patients with bronchiectasis?
The study was designed as a randomized controlled trial. Participants were divided into two groups: intervention and control.
Participants will:
The intervention group will receive HIIE training three days a week along with airway clearance techniques.
The control group would receive only airway clearance techniques. Airway clearance techniques will be provided clinically (three days a week) and at home, according to the needs of the individuals each day of the week.
The 2 groups in the trial
- InterventionExisting treatment, for comparison
Patients in this group will perform airway clearance techniques along with high-intensity interval exercise.
Treatment: high-intensity interval exercise and Airway clearance tecniques
- ControlExisting treatment, for comparison
Patients in this group will only undergo airway clearance techniques.
Treatment: Airway clearance tecniques
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Investigation of the Effectiveness of High-Intensity Interval Exercise in Bronchiectasis Patients
- Plain-language title
- High-intensity interval exercise added to airway clearance for people with bronchiectasisGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 4 September 2026