Collagen supplements, muscle mass and body image after weight-loss surgery
Looks at collagen supplement use in adults after sleeve gastrectomy for obesity.
Plain-language title generated from the registry record
Registry title: Collagen Supplements and Post-MBS Muscle Mass/Body Image
Key facts
- Where
- Bursa, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have had metabolic and bariatric surgery (sleeve gastrectomy) and are in regular follow-up. It compares people who choose to use collagen supplements with those who do not.
- Age
- 18 to 65 years
- Sex
- All sexes
- Disease stage
- BMI of 35 kg/m² or more, or BMI of 30-34.9 kg/m² with an obesity-related metabolic disease and considered fit for surgery. Must have had metabolic and bariatric surgery.
- Earlier treatment
- Must have had metabolic and bariatric surgery following current ASMBS/IFSO guidelines, and be under regular follow-up after the operation.
Main reasons for not taking part
- Inflammatory bowel disease
- History of upper gastrointestinal bleeding
- Severe psychiatric disorders
- Active cancer diagnosis
- Pregnancy or breastfeeding
Read by machine on 13 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07809152, who can take part
Where in Türkiye
- Yıldırım Doruk HastanesiBursa, TürkiyeContact: Seher Şen, Assistant ProfessorTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Mudanya University
- Trial code
- NCT07809152
- Record updated
- 9 September 2026
- Original description
This prospective, observational cohort study aims to evaluate whether the use of collagen-containing supplements is associated with differences in muscle mass, body composition, and body image among patients who have undergone sleeve gastrectomy (SG). The study will be conducted at the General Surgery outpatient clinic of a private hospital in Bursa, Türkiye, between May 2026 and March 2027, and will enroll adult patients (aged 18-65 years) who meet current ASMBS/IFSO eligibility criteria for metabolic and bariatric surgery.Read full original descriptionShow less
Relationship Between Collagen-Containing Supplement Use and Muscle Mass and Body Image Following Metabolic and Bariatric Surgery: A Prospective Observational Study
This prospective, observational cohort study aims to evaluate whether the use of collagen-containing supplements is associated with differences in muscle mass, body composition, and body image among patients who have undergone sleeve gastrectomy (SG). The study will be conducted at the General Surgery outpatient clinic of a private hospital in Bursa, Türkiye, between May 2026 and March 2027, and will enroll adult patients (aged 18-65 years) who meet current ASMBS/IFSO eligibility criteria for metabolic and bariatric surgery.
Participants will be naturally allocated into two observational groups based on their own choice to use or not use collagen-containing supplements; no supplement will be provided or recommended by the study team, and no intervention will be made to participants' standard clinical care. All patients will be followed according to routine clinical practice preoperatively and at 2 weeks, 1 month, 3 months, and 6 months postoperatively.
Primary outcome measures include anthropometric parameters (body weight, BMI, fat mass, fat mass percentage, fat-free mass, muscle mass, percentage of weight loss, percentage of excess weight loss, waist and hip circumference) assessed via bioelectrical impedance analysis (Tanita MC-780 MA), and body image assessed using the Turkish-validated Body Shape Questionnaire (BSQ). Secondary outcomes include biochemical parameters, comorbidities, and macronutrient intake data obtained from 3-day dietary records analyzed using the BEBİS nutrition software.
The study hypothesizes that patients using collagen-containing supplements will show significant differences in muscle mass and body composition parameters compared with non-users, and that supplement use will be significantly associated with BSQ scores. A sample size of approximately 52 participants per group was calculated using G*Power 3.1 (one-way ANOVA, Cohen's f = 0.25, α = 0.05, power = 0.80).
Inclusion: Patients with a BMI ≥ 35 kg/m², regardless of the presence of comorbidities; Patients with a BMI of 30-34.9 kg/m² who have an obesity-related metabolic disease and are considered eligible for surgical treatment; Patients who have undergone metabolic and bariatric surgery (MBS) in accordance with current ASMBS/IFSO guidelines (Eisenberg et al., 2022); Patients under regular postoperative follow-up; Age 18-65 years.
Exclusion: Inflammatory bowel disease; History of upper gastrointestinal bleeding; Severe psychiatric disorders; Active cancer diagnosis; Pregnancy or breastfeeding; Alcohol or substance dependence; Physical limitations preventing participation in exercise.