Lidocaine infusion added to a nerve block for pain relief during gastric bypass surgery
Tests added lidocaine infusion for pain control in adults having gastric bypass surgery.
Plain-language title generated from the registry record
Registry title: External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery
Key facts
- Where
- Alexandria, EgyptSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07809425, who can take part
Where in Egypt
- Faculty of MedicineAlexandria, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Menoufia University
- Trial code
- NCT07809425
- Record updated
- 11 September 2026
- Original description
Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing adverse events.Read full original descriptionShow less
External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery: a Randomized Controlled Trial
Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing adverse events.
Inclusion: Age 18-60 years; BMI ≥ 35 kg/m²; ASA physical status II or III; Scheduled for elective laparoscopic Roux en Y gastric bypass; Ability to provide written informed consent.
Exclusion: Allergy or contraindication to lidocaine, fentanyl, ropivacaine, or any study medication; Coagulopathy, anticoagulation incompatible with regional anesthesia, or infection at block site; Severe psychiatric or cognitive disorder; Significant hepatic (AST/ALT> 3× normal, cirrhosis) or renal impairment (CrCl< 30 mL/min); Refusal; Chronic opioid use or dependence; Second or third degree AV block or significant bradyarrhythmia without pacemaker; Pregnancy or lactation; Failed bilateral EOIB (absence of sensory loss in T6-T10 after 30 min) - excluded from analysis.