Benzhexol versus procyclidine for tremor in Parkinson's disease
Compares benzhexol and procyclidine for tremor in adults with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's Disease
Key facts
- Where
- Lahore, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 70 years old?
Source: NCT07810296, who can take part
Where in Pakistan
- Mayo Hospital LahoreLahore, PakistanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- safia bano
- Trial code
- NCT07810296
- Record updated
- 14 September 2026
- Original description
The goal of this clinical trial is to compare benzhexol and procyclidine for improving tremor in adults with tremor-predominant Parkinson's disease who are taking levodopa. Researchers will compare the two medicines to determine whether benzhexol provides similar improvement in tremor to procyclidine and to assess their side effects. Participants will be randomly assigned to receive either benzhexol or procyclidine in addition to their usual levodopa treatment. Motor symptoms and side effects will be assessed before treatment and at 2 weeks, 3 months, and 6 months.Read full original descriptionShow less
Comparison of Effectiveness of Benzhexol and Procyclidine in Improving Tremor in Tremor Predominant Parkinson's Disease Patients
The goal of this clinical trial is to compare benzhexol and procyclidine for improving tremor in adults with tremor-predominant Parkinson's disease who are taking levodopa. Researchers will compare the two medicines to determine whether benzhexol provides similar improvement in tremor to procyclidine and to assess their side effects. Participants will be randomly assigned to receive either benzhexol or procyclidine in addition to their usual levodopa treatment. Motor symptoms and side effects will be assessed before treatment and at 2 weeks, 3 months, and 6 months.
Inclusion: Diagnosed Parkinson's disease according to the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease, with predominant tremor at presentation; Hoehn and Yahr stage 1, 2, or 3; Any gender; Age 40 to 70 years; Receiving levodopa/carbidopa monotherapy for Parkinson's disease, with resting tremor present.
Exclusion: Cardiac disease; Cognitive or behavioral abnormalities; Lower urinary tract symptoms; Benign prostatic hyperplasia; Angle-closure glaucoma.