Burning scar channel exits to treat ventricular tachycardia in people with heart scarring
Studies targeted ablation of scar channel exits in adults with ventricular tachycardia.
Key facts
- Who runs it
- New York Medical College
- Where
- Valhalla, United StatesSee the site
- Trial code
- Registry title
- Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia
- Status
- Recruiting
- People taking part
- 30 people, planned
- Started
- 27 Mar 2025
- Expected to end
- 9 Dec 2028
- Type of study
- Observational
- Treatments tested
- Selective Substrate Isolation
- Record updated
- 10 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with structural heart disease who are having an ablation procedure for ventricular tachycardia (VT), a fast, abnormal heart rhythm. It tests targeted ablation of scar channels that cause VT.
- Age
- 18 Years and older
- Sex
- All sexes can join.
- Disease stage
- Structural heart disease, such as ischemic or nonischemic cardiomyopathy, with VT, and scheduled for VT ablation.
Main reasons for not taking part
- Unable or unwilling to sign consent.
- Cardiogenic shock (very low heart pumping) or NYHA Class IV heart failure, when the person cannot have mechanical heart support (percutaneous LVAD, extracorporeal membrane oxygenation, or implanted LVAD) for the procedure.
- No scar tissue found during the first voltage mapping of the heart.
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Patients with structural heart disease undergoing VT ablation
Who cannot take part
- Cardiogenic shock or NYHA Class IV heart failure and not a candidate for mechanical circulatory support for the procedure (percutaneous left ventricular assist device (LVAD), extracorporeal membrane oxygenation, or implanted LVAD)
- Unable or unwilling to sign consent
- Absence of substrate during initial voltage mapping
Where in United States
- Westchester Medical CenterValhalla, United StatesContact: Jason T Jacobson, MDTaking people
About the trial
What the trial wants to find out
The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to block these channels from causing VT with targeted radiofrequency ablation (cautery).
Read full original descriptionShow less
Participants undergoing VT ablation mapping of these channels by pacing many sites within the scar area and determining where these channels exit the scar into normal tissue. These exits will be ablated. Immediate success and success at 1 year will be evaluated.
Treatments tested
- Selective Substrate Isolation
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Segmental Substrate Isolation for the Treatment of Ventricular Tachycardia in Patients With Structural Heart Disease
- Plain-language title
- Burning scar channel exits to treat ventricular tachycardia in people with heart scarringGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 10 September 2026