Studies atypical endometriosis lesions using ultrasound and biological features
Compares tissue, ultrasound and molecular features of atypical and typical endometriosis in adults.
Plain-language title generated from the registry record
Registry title: Study on the Ultrasound and Biological Characteristics of Atypical Endometriosis.
Key facts
- Where
- Peschiera del Garda, ItalySee the site
Where in Italy
- Ospedale P. Pederzoli Casa di Cura Privata S.p.A.Peschiera del Garda, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Casa di Cura Dott. Pederzoli
- Trial code
- NCT07816133
- Record updated
- 11 September 2026
- Original description
This study hypothesizes that the histological, immunophenotypic, and molecular characterization of atypical endometriotic lesions may be related to specific clinical and ultrasound features.Identifying potentially atypical lesions would allow for more accurate stratification of patients, distinguishing definitely benign from potentially atypical endometriosis.Read full original descriptionShow less
Endometriosis "Atypical" and Cancerized: Anatomopathological and Clinical-instrumental Characterization on the Ultrasound and Biological Characteristics of Atypical Endometriosis.
This study hypothesizes that the histological, immunophenotypic, and molecular characterization of atypical endometriotic lesions may be related to specific clinical and ultrasound features.Identifying potentially atypical lesions would allow for more accurate stratification of patients, distinguishing definitely benign from potentially atypical endometriosis.
The targeted study of endometriosis, both typical and atypical, also with reference to the inflammatory microenvironment, as well as immunophenotypic and molecular characteristics, could allow the formulation of pathogenic hypotheses on the development and progression of atypia towards malignant neoplasms.
Inclusion: Age > 18 years; Candidate patients for endometriosis surgery with deep endometriosis (intestine, LUS) and/or endometrioma localizations; Patients who are candidates for surgery for established or suspected endometrial and/or ovarian neoplasm; Patients who have performed a level II gynecological ultrasound with an experienced operator in the preoperative process; Patients where there is the technical possibility of performing a transvaginal and/or transrectal ultrasound and the patient's willingness to undergo such an investigation; Signing of informed consent.
Exclusion: Previous neoplasms; Technical impossibility of performing a transvaginal ultrasound (patient virgo, patient refusal); Patient who does not provide their informed consent.