Heart monitoring devices to detect atrial fibrillation in people with heart failure
Tests heart rhythm monitors in adults with heart failure and no atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure Patients
Key facts
- Where
- Enschede, NetherlandsSee the site
Where in Netherlands
- Medisch Spectrum TwenteEnschede, NetherlandsNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medisch Spectrum Twente
- Trial code
- NCT07816458
- Record updated
- 10 November 2026
- Original description
The goal of this clinical trial is to learn if using remote heart rhythm monitoring strategies can reduce unplanned cardiac care utilization and improve health-related quality of life in adults with heart failure (HF). It focuses on adults with heart failure who have no history of an irregular heartbeat called atrial fibrillation (AF) and do not have an existing pacemaker or implantable defibrillator.Read full original descriptionShow less
Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure Patients
The goal of this clinical trial is to learn if using remote heart rhythm monitoring strategies can reduce unplanned cardiac care utilization and improve health-related quality of life in adults with heart failure (HF). It focuses on adults with heart failure who have no history of an irregular heartbeat called atrial fibrillation (AF) and do not have an existing pacemaker or implantable defibrillator.
The main questions the trial aims to answer are:
* Does a continuous rhythm monitor placed under the skin or a patient-driven portable home device decrease unplanned cardiac care utilization? * Do these rhythm monitoring strategies influence therapeutic management? * Do these rhythm monitoring strategies improve patient-reported quality of life and overall survival?
Researchers will compare two monitoring groups to a standard care group over an 18-month period to see which approach works best in heart failure treatment
Participants will:
* either have a small heart monitor placed under their chest skin for heart rhythm observation (arm 1), use a handheld device to take regular heart recordings at home (arm 2) or follow standard care (arm 3) for a period of 18 months * Answer a health survey at the start of the study and after 18 months of follow-up.
Inclusion: Adult patients with HF and no history of documented AF on electrocardiogram (ECG).
Exclusion: Patients with CIED, such as an implantable cardioverter defibrillator (ICD), Cardiac Resynchronization Therapy Defibrillator (CRT-D), or pacemaker; Mental disorders that, according to the treating physician, make participation unsafe; Participant under the age of 18 years old; Documented AF before inclusion; Admission to hospices or palliative care; Inability to communicate in Dutch or English; Participant is pregnant.