Keeping Donor Hearts at 10 Degrees C During Heart Transplant
Tests a cooler that stores donor hearts at 10°C for adults receiving transplants.
Plain-language title generated from the registry record
Registry title: 10 Degree C Static Storage in Heart Transplantation
Key facts
- Where
- Nashville, United StatesSee the site
Where in United States
- Vanderbilt University Medical CenterNashville, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- John Trahanas
- Trial code
- NCT07818941
- Record updated
- 14 September 2026
- Original description
The goal of this clinical trial is to conduct a feasibility investigation evaluating the preliminary safety and effectiveness of using the X°Port Heart Preservation System (XHPS) for 10°C preservation in clinical heart transplantation.Read full original descriptionShow less
Feasibility Study of 10 Degree C Static Storage in Human Heart Transplantation
The goal of this clinical trial is to conduct a feasibility investigation evaluating the preliminary safety and effectiveness of using the X°Port Heart Preservation System (XHPS) for 10°C preservation in clinical heart transplantation.
Participants will:
* undergo a standard heart transplant, with a donor heart preserved and transported at 10°C using the XHPS. * have data collected at key timepoints related to their recovery in the ICU and hospital * return after discharge for standard follow-up appointments, with capture of standard data collected
Recipient Inclusion Criteria:; Age >=18 years old; Listed for heart transplantation; Consented for the research study (signed Informed Consent Form); Recipient Exclusion Criteria:; Multi-organ transplant (i.e., heart-liver, heart-kidney, heart-lung); Previous solid organ or bone marrow transplant; Complex congenital etiology of heart failure; Donor Inclusion Criteria:; Donation after brain death or donation after circulatory death heart donors; Donor hearts that have been allocated to VUMC as a primary match offer prior to organ procurement will be eligible; Donor Exclusion Criteria:; Donor hearts that have been allocated to VUMC as a backup offer; Donor hearts that have been allocated to VUMC as a post-procurement offer; Donor hearts that have already been placed on ice.