NCT07819253Completed
Laser Photocoagulation and Ranibizumab Treatment in Proliferative Diabetic Retinopathy
Pan-Retinal Photocoagulation With Intravitreal Ranibizumab In Treatment Of Proliferative Diabetic Retinopathy
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
To evaluate the effects of PRP as monotherapy or with combination of intravitreal Ranibizumab injection on microvascular density changes of the macula of eyes with PDR using OCTA
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 9 Sept 2026
- Start date
- 1 Jul 2023
- Primary completion date
- 1 Jul 2025
- Lead sponsor
- Aswan University
- Diseases
- Diabetic eye disease
- NCT number
- NCT07819253
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 1 Jul 2023 to the primary completion date, 1 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- a) History of previous intra ocular surgery, uveitis, glaucoma and significant eye trauma.
- Significant media opacity decreasing image quality (corneal opacity, dense cataract, and vitreous hemorrhage)
- Significant macular edema to overcome errors in segmentation
- Scans with low signal strength index (SSI; \< 50), presence of blink artifacts, and poor fixation leading to motion artifacts.
- History of previous treatment for diabetic retinopathy including intravitreal injection of anti-VEGFs, laser, or vitrectomy
- Presence of vitreo-macular traction
Who the study is looking for
- PDR patients diagnosed clinically and by the presence of neovascularization on optic disc (NVDs) or elsewhere (NVEs) on fluorescein angiography.
Age in the registry: 30 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aswan University Hospital Coordinator of this site? Confirm its status | Aswān | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.