Growing 3D tumor models from kidney, bladder and prostate cancer patients
Collects blood samples to build 3D tumor models for urological cancer patients.
Plain-language title generated from the registry record
Registry title: Development of a Preclinical 3D Vascularized and Perfused Tumoroid Model in Oncology and Urology Developed From Patient Tumors (Kidney, Bladder, and Prostate Cancers)
Key facts
- Where
- Strasbourg, FranceSee the site
Where in France
- Service de Chirurgie Urologique _ Hôpitaux Universitaires de StrasbourgStrasbourg, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Strasbourg, France
- Trial code
- NCT07820566
- Record updated
- 15 September 2026
- Original description
This is a study :Read full original descriptionShow less
Development of a Preclinical 3D Vascularized and Perfused Tumoroid Model in Oncology and Urology Developed From Patient Tumors (Kidney, Bladder, and Prostate Cancers)
This is a study :
* Single-center * Prospective * Translational * Based on data and blood samples. In this context, the aim is to collect approximately 10 ml of blood from each patient included in the 3D tumoroid development project.
The main objective is to establish and validate a panel of vascularized and perfused 3D tumoroids for personalized medicine based on patient tumors for urological cancers, incorporating autologous immune cells.
Translated with DeepL.com (free version)
Inclusion: Criteria common to all patients:; Male or female subject (≥18 years old); Diagnosed with kidney cancer, prostate cancer, or bladder cancer; whose tumor tissue and associated data are reused as part of the SphéroUro protocol (study outside the Jardé law, retrospective study on tumor tissue and associated data, from the biobank registered with the Ministry of Education and Research under reference No. DC 2016-2677); affiliated with a social security health insurance scheme or beneficiary of such a scheme; agreeing to participate in the 3DBlood study; Specific criteria for patients with renal cell carcinoma (RCC):; Extended nephrectomy (EN) (larger tumor, closer to the sinus; therefore at greater risk of metastasis): with a cavo, cavectomy (neoplastic thrombus in the vena cava), or renal vein bud, or lymph node dissection, or with adrenalectomy (often for tumors, therefore possible metastases); Or; Partial nephrectomy (PN): with tumors at stage T2 or T3a).
Exclusion: Patient currently participating in a therapeutic clinical trial (i.e., gene therapy or other); Patient refusal to participate in the study; Inability to provide the subject with informed consent (subject in an emergency situation, difficulties in understanding the subject, etc.); Patient under legal protection, guardianship, or conservatorship.