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Comparing one-handed and two-handed skill learning with robots after stroke

Tests robot-based arm training, one hand versus both hands, in people after stroke.

Plain-language title generated from the registry record
Registry title: Unimanual Versus Bimanual Motor Skill Learning in Acute and Chronic Stroke

Key facts

Where
Yvoir, BelgiumSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 90 years old?

Source: NCT07826832, who can take part

Where in Belgium

  • Chu Ucl NamurYvoir, BelgiumTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University Hospital of Mont-Godinne
Trial code
NCT07826832
Record updated
17 September 2026
Original description
To test the capacity of healthy individuals, chronic and acute stroke patients to learn and retain a complex unimanual or bimanual motor skill, trained on the neurorehabiliation robot REAplan® et the Dextrain® device. The goals are (1) to compare head-to-head bimanual versus unimanual motor learning (in the proximal and distal upper limb, UL) during the acute - early subactue stage of stroke with robotics and (2) to identify the neural substrates associated with (and deficits in) unimanual versus bimanual motor control (proximal and distal) after stroke by means of multimodal brain imaging.Read full original descriptionShow less

Comparison of Unimanual Versus Bimanual Motor Skill Learning (Proximal and Distal) After Stroke by Means of Robotics (REA²Plan® and Dextrain®) and Multimodal Brain Imaging (VLSM, DTI, NODDI, DIAMOND)

To test the capacity of healthy individuals, chronic and acute stroke patients to learn and retain a complex unimanual or bimanual motor skill, trained on the neurorehabiliation robot REAplan® et the Dextrain® device. The goals are (1) to compare head-to-head bimanual versus unimanual motor learning (in the proximal and distal upper limb, UL) during the acute - early subactue stage of stroke with robotics and (2) to identify the neural substrates associated with (and deficits in) unimanual versus bimanual motor control (proximal and distal) after stroke by means of multimodal brain imaging.

Inclusion: acute stroke (between day 2 and day 21 post-stroke) or chronic stroke (>6 mois); aged 40-90 years; with a single demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging; 40-90 years.

Exclusion: drug/alcohol abuse; medical history with a previous stroke/relevant neurological deficit; drug/alcohol abuse; multiple stroke/dementia/psychiatric condition; HEALTHY INDIVIDUALS; psychiatric condition/dementia; [for acute paitents] "classical" contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...); difficulty in understanding or executing commands; severe aphasia/cognitive deficits interfering with study; inability to complete the tasks (i.e. full paralysis of the arm); "classical" contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...); having already used the robotic devices.

STROKE PATIENTS.

ClinicalTrials.gov NCT07826832