Blood test and questionnaire to find unrecognised chronic heart failure in adults over 40
Tests whether a blood test and a questionnaire can detect chronic heart failure.
Key facts
- Who runs it
- French Cardiology Society
- Where
- Nîmes and Poitiers, FranceSee the 2 sites
- Trial code
- Registry title
- Evaluation of the Clinical Value of NT-proBNP (or BNP) Measurement, Alone or in Combination With the EPOF Questionnaire, for the Screening of Chronic Heart Failure (CHF) in Adults Aged 40 Years and Older Referred for a Cardiology Consultation Without Suspected CHF.
- Status
- Not yet recruiting
- People taking part
- 1,000 people, planned
- Started
- Sept 2026
- Expected to end
- Apr 2027
- Type of study
- Observational
- Record updated
- 23 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 40 to 80 who are sent to a cardiology consultation for a reason other than suspected chronic heart failure. They must not already have a heart failure diagnosis.
- Age
- 40 to 80 years
- Sex
- All sexes can join.
- Disease stage
- People without a known or suspected chronic heart failure diagnosis, referred for another cardiology reason.
Main reasons for not taking part
- Known diagnosis of chronic heart failure (CHF)
- Refusal to take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Adults aged 40 to 80 years
- Referred for a cardiology consultation for a reason other than suspected chronic heart failure or any of the four EPOF signs
- Informed about the study and not objecting to participation, in accordance with applicable regulations
Who cannot take part
- Known diagnosis of chronic heart failure (CHF)
- Refusal to participate
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 80 years old?
Where in France
- Private Cardiology PracticeNîmes, FranceContact: Marc VILLACEQUE, MDNo longer taking part
- Polyclinique de Poitiers - GCS ELSANPoitiers, FranceContact: Barnabas GELLEN, MDNo longer taking part
About the trial
What the trial wants to find out
This observational study aims to evaluate whether measuring NT-proBNP (or BNP), either on its own or alongside the EPOF questionnaire, can improve the early detection of chronic heart failure (CHF) in adults aged 40 years or over who are referred for an outpatient cardiology evaluation and have no known or suspected CHF.
Read full original descriptionShow less
The study will address the following questions:
Does systematic NT-proBNP (or BNP) testing help to identify previously unrecognised CHF? Does combining NT-proBNP (or BNP) with the EPOF questionnaire enhance diagnostic accuracy compared with using each tool alone? Participants will attend their routine cardiology consultation, complete the EPOF questionnaire and undergo NT-proBNP (or BNP) testing as part of the clinical assessment. They will also allow the collection of relevant medical data. The diagnostic performance of these tools will then be compared with the final diagnosis made by the outpatient cardiologist.
The study focuses on a population referred from primary care with increased cardiovascular risk. The early use of simple, accessible tools could reduce diagnostic delays, improve referral appropriateness and facilitate the earlier detection of CHF in general practice.
The group in the trial
- Adults ≥40 years referred for cardiology consultation without suspected chronic heart failure
Adults aged 40 years and older with no history of chronic heart failure (CHF), referred for a cardiology consultation at participating centers for reasons other than suspected CHF, and who underwent NT-proBNP or BNP measurement as part of routine clinical care. The biomarker measurement may have been performed before the consultation or ordered by the treating cardiologist during the consultation if considered clinically indicated, independently of study participation. The study does not require or mandate any additional NT-proBNP or BNP testing; participants are included only if a routine-care biomarker result is available.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluation of the Clinical Value of NT-proBNP (or BNP) Measurement, Alone or in Combination With the EPOF Questionnaire, for the Screening of Chronic Heart Failure (CHF) in Adults Aged 40 Years and Older Referred for a Cardiology Consultation Without Suspected CHF.
- Plain-language title
- Blood test and questionnaire to find unrecognised chronic heart failure in adults over 40Generated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07837349, who can take part
- Record updated
- 23 September 2026