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Giving tuberculosis treatment at community pharmacies for people with TB and HIV in Uganda

Tests getting tuberculosis treatment from community pharmacies in adults with both TB and HIV.

Plain-language title generated from the registry record
Registry title: Integrating Tuberculosis Treatment Into Community Pharmacies to Improve TB/HIV Outcomes in Uganda

Key facts

Where
Kampala, UgandaSee the 2 sites

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with both TB and HIV in Kampala, Uganda, who recently started TB treatment. It tests getting TB and HIV medicine refills at community pharmacies.

Age
18 years or older
Sex
Men and women can join.
Disease stage
Drug-susceptible TB of the lungs, confirmed by tests or diagnosed clinically.
Earlier treatment
Must be on a first-line ART regimen or its alternative, and must have received TB treatment for 2 months or less.

Main reasons for not taking part

  • TB outside the lungs (extrapulmonary TB), because treatment often lasts over 6 months
  • People likely to move to other health facilities

This trial only enrols participants living with HIV. The registry sentence this rests on: * People with TB/HIV aged ≥18 years, receiving treatment for bacteriologically confirmed or clinically diagnosed drug-susceptible pulmonary TB, on a first-line ART regimen or its alternative, and receiving TB treatment for ≤2 months.

Read by machine on 13 November 2026.

Where in Uganda

  • Kawaala HC IIIKampala, UgandaContact: Mark Muhumuza, MDNo longer taking part
  • Kisenyi HC IVKampala, UgandaContact: Mary Ichumar, BNSNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Makerere University
Trial code
NCT07840651
Record updated
25 September 2026
Original description
Community pharmacies (CPs) have emerged as promising differentiated service delivery models for refilling antiretroviral therapy (ART) among people with human immunodeficiency virus (HIV). Documented benefits of CP-based refills include improved treatment adherence and viral suppression, reduced healthcare provider workload, and reduced facility congestion. This trial will evaluate the acceptability, feasibility, fidelity, and preliminary effectiveness of integrating TB treatment into CPs among people with TB/HIV in Kampala, Uganda.Read full original descriptionShow less

Integrating Tuberculosis Treatment Into Community Pharmacies for People With TB/HIV in Kampala, Uganda: a Pilot Randomized Trial With a Type 2 Hybrid Design

Community pharmacies (CPs) have emerged as promising differentiated service delivery models for refilling antiretroviral therapy (ART) among people with human immunodeficiency virus (HIV). Documented benefits of CP-based refills include improved treatment adherence and viral suppression, reduced healthcare provider workload, and reduced facility congestion. This trial will evaluate the acceptability, feasibility, fidelity, and preliminary effectiveness of integrating TB treatment into CPs among people with TB/HIV in Kampala, Uganda.

Inclusion: People with TB/HIV aged ≥18 years, receiving treatment for bacteriologically confirmed or clinically diagnosed drug-susceptible pulmonary TB, on a first-line ART regimen or its alternative, and receiving TB treatment for ≤2 months.

Exclusion: Individuals with extrapulmonary TB as their treatment often exceeds 6 months, and those likely to transfer to other health facilities.

ClinicalTrials.gov NCT07840651