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Taking people in PakistanPhase 4

Two types of back anesthesia compared for men having prostate surgery through the urethra

Compares modified saddle block with spinal anesthesia in people having prostate surgery.

Plain-language title generated from the registry record
Registry title: Modified Saddle Block vs Spinal Anesthesia for TURP

Key facts

Where
Islamabad, PakistanSee the site
Phase
Phase 4

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for men aged 40 to 90 years who are having planned prostate surgery (TURP) under spinal-type anesthesia. It compares two ways of giving the anesthesia.

Age
40 to 90 years
Sex
Men only
Disease stage
Planned (elective) TURP surgery under neuraxial anesthesia; ASA class I and II

Main reasons for not taking part

  • Contraindication to neuraxial anesthesia
  • Allergy to the study medications
  • Lack of consent

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 90 years old?

Source: NCT07841184, who can take part

Where in Pakistan

  • Deparmtent of Anesthesia and Critical Care Medicine, Pakistan Institute of Medical SciencesIslamabad, PakistanContact: Naheed Fatima Head of Department, MBBS,FCPS,MHPETaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Pakistan Institute of Medical Sciences
Trial code
NCT07841184
Record updated
25 September 2026
Original description
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded. Participants will be randomly assigned to receive either spinal anesthesia or a modified saddle block using hyperbaric bupivacaine administered in the lower back. The position of the patient after injection will differ according to the assigned anesthetic technique. The level of numbness produced by the anesthesia will be assessed, and patients with inadequate anesthesia will be excluded. Blood pressure and heart rate will be monitored regularly during surgery. Any significant decrease in blood pressure will be treated with intravenous phenylephrine. Any need to change to general anesthesia during the procedure will also be recorded.Read full original descriptionShow less

Comparison of Modified Saddle Block With Spinal Anesthesia Among Patients Undergoing Transurethral Resection of Prostate Cancer; A Randomized Control Trial at a Tertiary Care Hospital

After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded. Participants will be randomly assigned to receive either spinal anesthesia or a modified saddle block using hyperbaric bupivacaine administered in the lower back. The position of the patient after injection will differ according to the assigned anesthetic technique. The level of numbness produced by the anesthesia will be assessed, and patients with inadequate anesthesia will be excluded. Blood pressure and heart rate will be monitored regularly during surgery. Any significant decrease in blood pressure will be treated with intravenous phenylephrine. Any need to change to general anesthesia during the procedure will also be recorded.

Inclusion: Age 40- 90 years; Elective TURP surgery under Neuraxial Anesthesia; ASA class I and II.

Exclusion: Allergic to study medications; Contraindication to Neuraxial anesthesia; Lack of consent.

ClinicalTrials.gov NCT07841184