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Fitness After Lung Cancer Surgery: Removing a Lobe Versus a Smaller Part

Compares exercise fitness after two kinds of lung surgery in adults with lung cancer.

Plain-language title generated from the registry record
Registry title: Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection

Key facts

Where
Wuhan, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with lung cancer who can have lung surgery (lobectomy, segmentectomy or wedge resection). It compares fitness after the two kinds of surgery.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Lung cancer (NSCLC) where lung surgery is planned and judged tolerable after heart and lung testing.

Main reasons for not taking part

  • Pregnant or breastfeeding
  • Any absolute contraindication to cardiopulmonary exercise testing (CPET)
  • Severe heart disease, heart failure, heart attack or angina in the previous 3 months
  • Stroke or brain bleed in the previous 3 months
  • Psychiatric illness that prevents communication, or unable to cooperate with the examinations

Read by machine on 12 November 2026.

Where in China

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, ChinaContact: Wei PingTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Tongji Hospital
Trial code
NCT07841249
Record updated
25 September 2026
Original description
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection. Patients who can undergo pulmonary resection and meet the eligibility criteria will be studied during routine clinical care; the research will not assign the surgical procedure or add a study-specific intervention.Read full original descriptionShow less

Impact of Lobectomy Versus Sublobar Resection on Cardiorespiratory Fitness: An Observational Study Based on Cardiopulmonary Exercise Testing

This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection. Patients who can undergo pulmonary resection and meet the eligibility criteria will be studied during routine clinical care; the research will not assign the surgical procedure or add a study-specific intervention.

Cardiopulmonary exercise testing (CPET) and pulmonary function testing will be performed before surgery and at routine follow-up visits 6 and 12 months after surgery. Changes from the preoperative assessment will be compared within each surgical group and between the two groups. The study will also examine the relationship between CPET measurements and postoperative complications.

Inclusion: Able to understand the study and provide written informed consent. 2. Considered able to tolerate surgical treatment, including segmentectomy, lobectomy, or wedge resection, following preoperative assessment, including cardiac and pulmonary function testing; -.

Exclusion: A history of severe heart disease, heart failure, myocardial infarction, or an episode of angina within the previous 3 months; A cerebrovascular event, including cerebral infarction or cerebral hemorrhage, within the previous 3 months; A psychiatric illness that prevents communication; Pregnant or breastfeeding; Any absolute contraindication to CPET; Unable to cooperate with the examinations. -.

ClinicalTrials.gov NCT07841249